Ibukuro Kenji, Takeguchi Takaya, Fukuda Hozumi, Mori Masaya, Abe Shoko, Tobe Kimiko
Mitsui Memorial Hospital, Tokyo, Japan
Mitsui Memorial Hospital, Tokyo, Japan.
Acta Radiol. 2015 Sep;56(9):1091-9. doi: 10.1177/0284185114549824. Epub 2014 Sep 26.
Although the clinical presentation of intramural hematoma (IMH) and aortic double-lumen dissection (AD) is similar, the imaging results and subsequent clinical course of the two lesions differ.
To compare the clinical and radiological findings of IMH, AD, and mixed type lesions.
Forty-two patients with IMH, 38 with AD, and 10 with mixed type lesions were imaged with post-contrast-enhanced CT. The most proximal ulcer-like lesions and entry tears and the distal ends of the IMH and AD were evaluated. The interval change of the intramural hematoma, ulcer-like lesion, and false lumen was observed. The pathological findings of the aorta were evaluated in 15 patients.
The most proximal ulcer-like lesion and entry tear were located in the arch to the descending aorta in 27 (64.2%) of the 42 patients with IMH and in 24 (63.1%) of the 38 patients with AD. The distal extension was located at the iliac arteries in six (14.3%) patients with IMH and in 31 (81.6%) patients with AD (P < 0.001). The intramural hematomas regressed in 29 (93.5%) of 31 patients, and the ulcer-like lesion progressed in 14 (70%) of 20 patients with IMH. The clinical features of the mixed type lesions resembled those of AD, rather than IMH. The intramural hematoma or dissection was observed within the outer media in all lesion types on histopathology.
There is a distinct difference between IMH and AD in distal extension; however, the locations of the lesions are pathologically the same in the media of the aorta.
尽管壁内血肿(IMH)和主动脉双腔夹层(AD)的临床表现相似,但这两种病变的影像学结果及后续临床病程有所不同。
比较IMH、AD及混合型病变的临床和影像学表现。
对42例IMH患者、38例AD患者及10例混合型病变患者进行增强CT检查。评估最近端的溃疡样病变、破口及IMH和AD的远端。观察壁内血肿、溃疡样病变及假腔的间隔变化。对15例患者的主动脉病理结果进行评估。
42例IMH患者中,27例(64.2%)最近端的溃疡样病变和破口位于主动脉弓至降主动脉;38例AD患者中,24例(63.1%)位于此处。6例(14.3%)IMH患者的远端延伸至髂动脉,31例(81.6%)AD患者的远端延伸至髂动脉(P < 0.001)。31例患者中,29例(93.5%)的壁内血肿消退,20例IMH患者中,14例(70%)的溃疡样病变进展。混合型病变的临床特征更类似于AD,而非IMH。组织病理学检查显示,所有病变类型的壁内血肿或夹层均见于外中膜。
IMH和AD在远端延伸方面存在明显差异;然而,在主动脉中膜,这些病变的位置在病理上是相同的。