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1
Proteopathic tau seeding predicts tauopathy in vivo.
Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):E4376-85. doi: 10.1073/pnas.1411649111. Epub 2014 Sep 26.
2
Sensitive Detection of Proteopathic Seeding Activity with FRET Flow Cytometry.
J Vis Exp. 2015 Dec 8(106):e53205. doi: 10.3791/53205.
3
Characterization of tau prion seeding activity and strains from formaldehyde-fixed tissue.
Acta Neuropathol Commun. 2017 Jun 7;5(1):41. doi: 10.1186/s40478-017-0442-8.
4
Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples.
J Biol Chem. 2019 Nov 1;294(44):16451-16464. doi: 10.1074/jbc.RA119.009688. Epub 2019 Sep 19.
6
FRET and Flow Cytometry Assays to Measure Proteopathic Seeding Activity in Biological Samples.
Methods Mol Biol. 2017;1523:349-359. doi: 10.1007/978-1-4939-6598-4_23.
7
Extracellular Vesicles Isolated from the Brains of rTg4510 Mice Seed Tau Protein Aggregation in a Threshold-dependent Manner.
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10
Conformation determines the seeding potencies of native and recombinant Tau aggregates.
J Biol Chem. 2015 Jan 9;290(2):1049-65. doi: 10.1074/jbc.M114.589309. Epub 2014 Nov 18.

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2
Polyserine-mediated targeting of FAF2/UBXD8 ameliorates tau aggregation.
Neuron. 2025 Aug 29. doi: 10.1016/j.neuron.2025.08.002.
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Systematic characterization of cell type-specific master metabolic regulators in Alzheimer's disease.
Res Sq. 2025 Aug 18:rs.3.rs-7207381. doi: 10.21203/rs.3.rs-7207381/v1.
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Lysine-Targeting Inhibitors of Amyloidogenic Protein Aggregation: A Promise for Neurodegenerative Proteinopathies.
JACS Au. 2025 Aug 11;5(8):3680-3700. doi: 10.1021/jacsau.5c00269. eCollection 2025 Aug 25.
9
Cell type-specific master metabolic regulators of Alzheimer's disease.
bioRxiv. 2025 Jul 17:2025.07.11.664443. doi: 10.1101/2025.07.11.664443.
10
Tau uptake by human neurons depends on receptor LRP1 and kinase LRRK2.
EMBO J. 2025 Aug 11. doi: 10.1038/s44318-025-00514-0.

本文引用的文献

2
Prion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic target.
J Biol Chem. 2014 Jul 18;289(29):19855-61. doi: 10.1074/jbc.R114.549295. Epub 2014 May 23.
3
Distinct tau prion strains propagate in cells and mice and define different tauopathies.
Neuron. 2014 Jun 18;82(6):1271-88. doi: 10.1016/j.neuron.2014.04.047. Epub 2014 May 22.
4
Detection of misfolded Aβ oligomers for sensitive biochemical diagnosis of Alzheimer's disease.
Cell Rep. 2014 Apr 10;7(1):261-8. doi: 10.1016/j.celrep.2014.02.031. Epub 2014 Mar 20.
5
Neuronal activity regulates extracellular tau in vivo.
J Exp Med. 2014 Mar 10;211(3):387-93. doi: 10.1084/jem.20131685. Epub 2014 Feb 17.
7
Extracellular monomeric tau protein is sufficient to initiate the spread of tau protein pathology.
J Biol Chem. 2014 Jan 10;289(2):956-67. doi: 10.1074/jbc.M113.515445. Epub 2013 Nov 14.
8
Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo.
Neuron. 2013 Oct 16;80(2):402-414. doi: 10.1016/j.neuron.2013.07.046. Epub 2013 Sep 26.
10
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds.
Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):E3138-47. doi: 10.1073/pnas.1301440110. Epub 2013 Jul 29.

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