Murdoch Childrens Research Institute, Melbourne, Victoria, Australia; The Royal Children's Hospital, Melbourne, Victoria, Australia; Department of Paediatrics, The University of Melbourne, Melbourne, Victoria, Australia;
Discipline of Psychiatry, The University of Sydney, Sydney, Australia;
Pediatrics. 2014 Oct;134(4):e992-e1000. doi: 10.1542/peds.2014-1027.
To examine the functional status (mental health, academic performance, peer problems) of a community-based sample of children who have attention-deficit/hyperactivity disorder (ADHD) and non-ADHD controls, and to investigate gender and subtype differences.
Children aged 6 to 8 years were recruited through 43 Melbourne schools, using a 2-stage screening (parent and teacher Conners 3 ADHD index) and case confirmation (Diagnostic Interview Schedule for Children, Version IV; [DISC-IV]) procedure. Outcome measures were mental health disorders (DISC-IV), academic performance (Wide Range Achievement Test 4), and peer problems (Strength and Difficulties Questionnaire). Unadjusted and adjusted linear and logistic regression were used to compare ADHD and non-ADHD controls.
A total of 179 children who have ADHD and 212 non-ADHD controls were recruited. Compared with controls, children who had ADHD had higher odds of externalizing (odds ratio [OR], 11.0; 95% confidence interval [CI], 5.6-21.6; P < .001) and internalizing (OR, 2.9; 95% CI, 1.2-7.2; P = .02) disorders; poorer reading (effect size, -0.66) and mathematics (effect size, -0.69) performance; and more peer problems (P < .001). Boys and girls who had ADHD were equally impaired. Only 17% of children in our ADHD group had been previously diagnosed. Previous diagnosis was higher in the Combined group and for boys.
In their second year of school, children who had ADHD performed worse than controls across all functional domains, yet only a minority had been formally diagnosed with ADHD. Findings highlight the need for earlier diagnosis and intervention.
研究具有注意缺陷多动障碍(ADHD)和非 ADHD 对照的基于社区的儿童样本的功能状态(心理健康、学业成绩、同伴问题),并探讨性别和亚型差异。
通过 43 所墨尔本学校的 2 阶段筛查(家长和教师康纳斯 3 项 ADHD 指数)和病例确认(儿童诊断访谈表,第 4 版;[DISC-IV])程序,招募年龄在 6 至 8 岁的儿童。结局指标为精神健康障碍(DISC-IV)、学业成绩(广泛成就测试 4)和同伴问题(力量与困难问卷)。采用未调整和调整后的线性和逻辑回归比较 ADHD 和非 ADHD 对照组。
共招募了 179 名患有 ADHD 的儿童和 212 名非 ADHD 对照组。与对照组相比,患有 ADHD 的儿童出现外化问题的几率更高(优势比 [OR],11.0;95%置信区间 [CI],5.6-21.6;P <.001)和内化问题(OR,2.9;95% CI,1.2-7.2;P =.02);阅读(效应量,-0.66)和数学(效应量,-0.69)成绩更差;和更多的同伴问题(P <.001)。患有 ADHD 的男孩和女孩都受到同样的影响。我们 ADHD 组中只有 17%的儿童之前被诊断过。合并症组和男孩的诊断率更高。
在他们入学的第二年,患有 ADHD 的儿童在所有功能领域的表现都比对照组差,但只有少数儿童被正式诊断为 ADHD。研究结果强调了早期诊断和干预的必要性。