Koutsiaris Aristotle G
Clin Hemorheol Microcirc. 2015;61(3):429-38. doi: 10.3233/CH-141888.
The axial blood velocity (Vax) association with microvessel diameter (D) was studied at 104 different postcapillary venules (4 μm < D < 24 μm) and 30 different precapillary arterioles (6 μm≤D≤12 μm) in the human conjunctiva of normal healthy humans. Venular diameter sizes were classified as "very small" (Group 1, 4.4 μm≤D < 8.9 μm), "small" (Group 2, 8.9 μm≤D < 13.8 μm), "medium" (Group 3, 13.8 μm≤D < 19.1 μm) and "large" (Group 4, 19.1 μm≤D≤23.5). The Spearman's correlation coefficient (rs) in all 4 venular groups was less than 0.36 and not statistically significant (n = 26, p≥0.08). Similar correlation results were observed for the arteriolar group (rs) ≈ 0) for the peak systolic, the average and the end systolic axial velocities. Vax was significantly (p < 0.001) lower in Group 1 in comparison to that in Group 2 and significantly (p < 0.01) lower in Group 2 in comparison to that in Group 3. However, Vax was not significantly lower in Group 3 in comparison to that in Group 4. Average Vax and standard deviation was 0.48 ± 0.13, 0.64 ± 0.16, 0.82 ± 0.25 and 0.88 ± 0.32 mm/s for Groups 1, 2, 3 and 4 respectively. The above results reinforce the importance of measuring D in microvascular hemodynamics. Higher diameters suggest higher axial velocities but Vax does not change significantly within the limits of each of the aforementioned groups.
在正常健康人的人结膜中，研究了104条不同的毛细血管后微静脉（4μm＜D＜24μm）和30条不同的毛细血管前微动脉（6μm≤D≤12μm）中轴向血流速度（Vax）与微血管直径（D）的关系。微静脉直径大小分为“非常小”（第1组，4.4μm≤D＜8.9μm）、“小”（第2组，8.9μm≤D＜13.8μm）、“中”（第3组，13.8μm≤D＜19.1μm）和“大”（第4组，19.1μm≤D≤23.5）。所有4个微静脉组的斯皮尔曼相关系数（rs）均小于0.36，无统计学意义（n = 26，p≥0.08）。微动脉组在收缩期峰值、平均和收缩期末轴向速度方面观察到类似的相关结果（rs≈0）。与第2组相比，第1组的Vax显著降低（p＜0.001），与第3组相比，第2组的Vax显著降低（p＜0.01）。然而，与第4组相比，第3组的Vax没有显著降低。第1、2、3和4组的平均Vax和标准差分别为0.48±0.13、0.64±0.16、0.82±0.25和0.88±0.32mm/s。上述结果强化了在微血管血流动力学中测量D的重要性。直径越大，轴向速度越高，但在上述每组范围内，Vax变化不显著。
