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患有和未患有肺动脉高压的镰状细胞病患者的结膜和肺血流动力学特性

Conjunctival and pulmonary hemodynamic properties in sickle cell disease subjects with and without pulmonary hypertension.

作者信息

Kord Valeshabad Ali, Wanek Justin, Molokie Robert E, Machado Roberto F, Gordeuk Victor R, Shahidi Mahnaz

机构信息

Department of Ophthalmology and Visual Sciences University of Illinois at Chicago Chicago Illinois.

Department of Medicine Division of Hematology/Oncology University of Illinois at Chicago Chicago Illinois; Department of Biopharmaceutical Sciences University of Illinois at Chicago Chicago Illinois; Jesse Brown VA Medical Center Chicago Illinois.

出版信息

Clin Case Rep. 2015 Nov 6;3(12):1038-41. doi: 10.1002/ccr3.439. eCollection 2015 Dec.

DOI:10.1002/ccr3.439
PMID:26734142
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4693704/
Abstract

Conjunctival microvascular hemodynamic alterations were reported for the first time in sickle cell subjects with and without pulmonary hypertension. Assessment of the conjunctival microcirculation using noninvasive imaging may improve understanding of microvascular hemodynamic alterations that occur due to pulmonary hypertension in sickle cell disease.

摘要

首次报道了患有和未患有肺动脉高压的镰状细胞病患者的结膜微血管血流动力学改变。使用无创成像技术评估结膜微循环可能有助于更好地理解镰状细胞病中由肺动脉高压引起的微血管血流动力学改变。

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Clin Case Rep. 2015 Nov 6;3(12):1038-41. doi: 10.1002/ccr3.439. eCollection 2015 Dec.
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本文引用的文献

1
Conjunctival microvascular hemodynamics following vaso-occlusive crisis in sickle cell disease.镰状细胞病血管闭塞性危象后的结膜微血管血流动力学
Clin Hemorheol Microcirc. 2015 Sep 25;62(4):359-67. doi: 10.3233/CH-151977.
2
Feasibility of assessment of conjunctival microvascular hemodynamics in unilateral ischemic stroke.单侧缺血性卒中患者结膜微血管血流动力学评估的可行性
Microvasc Res. 2015 Jul;100:4-8. doi: 10.1016/j.mvr.2015.04.007. Epub 2015 Apr 24.
3
Conjunctival microvascular haemodynamics in sickle cell retinopathy.镰状细胞视网膜病变中的结膜微血管血流动力学
Acta Ophthalmol. 2015 Jun;93(4):e275-80. doi: 10.1111/aos.12593. Epub 2014 Nov 27.
4
Correlation of axial blood velocity to venular and arteriolar diameter in the human eye in vivo.人眼活体中轴向血流速度与小静脉和小动脉直径的相关性。
Clin Hemorheol Microcirc. 2015;61(3):429-38. doi: 10.3233/CH-141888.
5
Risk factors for death in 632 patients with sickle cell disease in the United States and United Kingdom.美国和英国632例镰状细胞病患者的死亡风险因素。
PLoS One. 2014 Jul 2;9(7):e99489. doi: 10.1371/journal.pone.0099489. eCollection 2014.
6
Echocardiography-derived tricuspid regurgitant jet velocity is an important marker for the progression of sickle-cell disease.超声心动图测定的三尖瓣反流射流速度是镰状细胞病进展的重要标志物。
Acta Haematol. 2014;132(2):152-8. doi: 10.1159/000357393.
7
Molecular mechanisms underlying synergistic adhesion of sickle red blood cells by hypoxia and low nitric oxide bioavailability.缺氧和低一氧化氮生物利用度协同黏附镰状红细胞的分子机制。
Blood. 2014 Mar 20;123(12):1917-26. doi: 10.1182/blood-2013-06-510180. Epub 2014 Jan 15.
8
Human bulbar conjunctival hemodynamics in hemoglobin SS and SC disease.血红蛋白 SS 和 SC 病患者的人球结膜血液动力学。
Am J Hematol. 2013 Aug;88(8):661-4. doi: 10.1002/ajh.23475. Epub 2013 Jun 12.
9
Hemodynamic predictors of mortality in adults with sickle cell disease.镰状细胞病成人死亡的血流动力学预测因素。
Am J Respir Crit Care Med. 2013 Apr 15;187(8):840-7. doi: 10.1164/rccm.201207-1222OC.
10
Feasibility of conjunctival hemodynamic measurements in rabbits: reproducibility, validity, and response to acute hypotension.兔结膜血流动力学测量的可行性：可重复性、有效性和对急性低血压的反应。
Microcirculation. 2012 Aug;19(6):521-9. doi: 10.1111/j.1549-8719.2012.00182.x.