Westhall Erik, Rosén Ingmar, Rossetti Andrea O, van Rootselaar Anne-Fleur, Kjaer Troels Wesenberg, Horn Janneke, Ullén Susann, Friberg Hans, Nielsen Niklas, Cronberg Tobias
BMC Neurol. 2014 Aug 16;14:159. doi: 10.1186/s12883-014-0159-2.
Electroencephalography (EEG) is widely used to assess neurological prognosis in patients who are comatose after cardiac arrest, but its value is limited by varying definitions of pathological patterns and by inter-rater variability. The American Clinical Neurophysiology Society (ACNS) has recently proposed a standardized EEG-terminology for critical care to address these limitations.
METHODS/DESIGN: In the TTM-trial, 399 post cardiac arrest patients who remained comatose after rewarming underwent a routine EEG. The presence of clinical seizures, use of sedatives and antiepileptic drugs during the EEG-registration were prospectively documented.
A well-defined terminology for interpreting post cardiac arrest EEGs is critical for the use of EEG as a prognostic tool.
The TTM-trial is registered at ClinicalTrials.gov (NCT01020916).
脑电图(EEG)被广泛用于评估心脏骤停后昏迷患者的神经学预后,但其价值受到病理模式定义的差异以及评分者间变异性的限制。美国临床神经生理学会(ACNS)最近提出了一种用于重症监护的标准化脑电图术语,以解决这些局限性。
方法/设计:在目标温度管理(TTM)试验中,399名心脏骤停后复温仍昏迷的患者接受了常规脑电图检查。前瞻性记录了脑电图记录期间临床癫痫发作的情况、镇静剂和抗癫痫药物的使用情况。
用于解释心脏骤停后脑电图的明确术语对于将脑电图用作预后工具至关重要。
TTM试验已在ClinicalTrials.gov(NCT01020916)注册。