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β-隐黄质作为维生素A的一个来源。

Beta-cryptoxanthin as a source of vitamin A.

作者信息

Burri Betty J

机构信息

Western Human Nutrition Research Center, USDA/ARS, CA, 95616, USA.

出版信息

J Sci Food Agric. 2015 Jul;95(9):1786-94. doi: 10.1002/jsfa.6942. Epub 2014 Nov 5.

DOI:10.1002/jsfa.6942
PMID:25270992
Abstract

Beta-cryptoxanthin is a common carotenoid that is found in fruit, and in human blood and tissues. Foods that are rich in beta-cryptoxanthin include tangerines, persimmons and oranges. Beta-cryptoxanthin has several functions that are important for human health, including roles in antioxidant defense and cell-to-cell communication. Most importantly, beta-cryptoxanthin is a precursor of vitamin A, which is an essential nutrient needed for eyesight, growth, development and immune response. We evaluate the evidence for beta-cryptoxanthin as a vitamin A-forming carotenoid in this paper. Observational, in vitro, animal model and human studies suggest that beta-cryptoxanthin has greater bioavailability from its common food sources than do alpha- and beta-carotene from theirs. Although beta-cryptoxanthin appears to be a poorer substrate for beta-carotene 15,15' oxygenase than is beta-carotene, animal model and human studies suggest that the comparatively high bioavailability of beta-cryptoxanthin from foods makes beta-cryptoxanthin-rich foods equivalent to beta-carotene-rich foods as sources of vitamin A. These results mean that beta-cryptoxanthin-rich foods are probably better sources of vitamin A, and more important for human health in general, than previously assumed.

摘要

β-隐黄质是一种常见的类胡萝卜素,存在于水果、人体血液和组织中。富含β-隐黄质的食物包括橘子、柿子和橙子。β-隐黄质具有多种对人体健康至关重要的功能,包括在抗氧化防御和细胞间通讯中的作用。最重要的是,β-隐黄质是维生素A的前体,而维生素A是视力、生长、发育和免疫反应所需的必需营养素。在本文中,我们评估了β-隐黄质作为一种形成维生素A的类胡萝卜素的证据。观察性研究、体外研究、动物模型研究和人体研究表明,β-隐黄质从其常见食物来源中的生物利用度高于α-胡萝卜素和β-胡萝卜素从它们常见食物来源中的生物利用度。尽管β-隐黄质似乎比β-胡萝卜素更不易成为β-胡萝卜素15,15'-加氧酶的底物,但动物模型研究和人体研究表明,β-隐黄质从食物中相对较高的生物利用度使富含β-隐黄质的食物作为维生素A的来源等同于富含β-胡萝卜素的食物。这些结果意味着,富含β-隐黄质的食物可能是比以前认为的更好的维生素A来源,总体上对人体健康也更重要。

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