Pant K K, Smith P A
Department of Pharmacology, University of Alberta, Edmonton, Alta., Canada.
Neurosci Lett. 1989 May 22;100(1-3):243-8. doi: 10.1016/0304-3940(89)90692-7.
The effects of atrial natriuretic factor (ANF) were investigated on rat and bullfrog sympathetic ganglia. Although there was little effect on neurones from rat superior cervical ganglion (SCG), B-cells in bullfrog paravertebral ganglia (BFSG) were depolarized. This depolarization was often associated with an increase in excitability and suppression of a voltage-dependent K+ current, the M-current (IM). ANF did not affect the amplitude of the nicotinic EPSP in either ganglion.
研究了心房利钠因子（ANF）对大鼠和牛蛙交感神经节的作用。虽然对大鼠颈上神经节（SCG）的神经元影响很小，但牛蛙椎旁神经节（BFSG）中的B细胞发生了去极化。这种去极化通常伴随着兴奋性增加和电压依赖性钾电流（M电流，IM）的抑制。ANF对这两种神经节中烟碱型兴奋性突触后电位（EPSP）的幅度均无影响。
