Akasu T, Hirai K, Koketsu K
Brain Res. 1983 Jan 10;258(2):313-7. doi: 10.1016/0006-8993(83)91157-5.
Adenosine triphosphate (ATP) depolarized the membrane of bullfrog sympathetic ganglion cells by decreasing resting K+ conductance. ATP also depressed the maximum amplitude of after-hyperpolarization of action potentials. Voltage-clamp study revealed that ATP markedly suppressed the TEA-insensitive K+ current which appeared to correspond to the M-current, while it affected less significantly on the delayed rectifier K+ current. It was suggested that ATP depolarized resting membrane by suppressing resting K+ conductances, including the M-current, and also depressed the after-hyperpolarization of action potentials by suppressing both the M-current and delayed rectifier K+ current.
三磷酸腺苷（ATP）通过降低静息钾离子电导使牛蛙交感神经节细胞膜去极化。ATP还降低了动作电位后超极化的最大幅度。电压钳研究表明，ATP显著抑制了似乎与M电流相对应的对四乙铵（TEA）不敏感的钾电流，而对延迟整流钾电流的影响较小。有人提出，ATP通过抑制包括M电流在内的静息钾离子电导使静息膜去极化，并且还通过抑制M电流和延迟整流钾电流来降低动作电位的后超极化。
