Zhang Junfeng, Xu Meiqing, Guo Mingfa, Mei Xinyu, Liu Changqing
Department of Thoracic Surgery, The Affiliated Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Sep;17(9):915-9.
To compare the effect of minimally invasive Ivor-Lewis esophagectomy with traditional Ivor-Lewis esophagectomy on the quality of life in patients with middle thoracic esophageal carcinoma.
Retrospective analysis was performed on 121 patients with middle thoracic esophageal carcinoma, of whom sixty patients underwent minimally invasive Ivor-Lewis esophagectomy(endoscopic group) and sixty-one patients underwent traditional Ivor-Lewis esophagectomy (open group). All the items of EORTC questionnaire QLQ-C30, seven items of QLQ-OES18 and two additional items(right upper limbs activity obstacle and numbness of right chest wall) were used to evaluate the quality of life.
The scores of global quality of life, physical functioning, role functioning, social functioning, fatigue, pain, dyspnea and troublesome coughing were more favourable in endoscopy group than those in open group at 4-week and 12-week after operation(P<0.05). However, the advantage of endoscopy group only sustained in global quality of life, physical functioning and fatigue at 24-week after operation(P<0.05). Furthermore, the scores of pain, right upper limbs activity obstacle and numbness of right chest wall were less in endoscopy group than those in open group at 4-week, 12-week and 24-week after operation.
Minimally invasive Ivor-Lewis esophagectomy is associated with less trauma, shorter time of recovery and better postoperative quality of life.
比较微创Ivor-Lewis食管癌切除术与传统Ivor-Lewis食管癌切除术对胸段中段食管癌患者生活质量的影响。
对121例胸段中段食管癌患者进行回顾性分析，其中60例患者接受了微创Ivor-Lewis食管癌切除术（内镜组），61例患者接受了传统Ivor-Lewis食管癌切除术（开放组）。采用欧洲癌症研究与治疗组织问卷QLQ-C30的所有项目、QLQ-OES18的7个项目以及另外2个项目（右上肢活动障碍和右胸壁麻木）来评估生活质量。
术后4周和12周时，内镜组的总体生活质量、身体功能、角色功能、社会功能、疲劳、疼痛、呼吸困难和咳嗽困扰评分均优于开放组（P<0.05）。然而，内镜组的优势仅在术后24周时在总体生活质量、身体功能和疲劳方面持续存在（P<0.05）。此外，术后4周、12周和24周时，内镜组的疼痛、右上肢活动障碍和右胸壁麻木评分均低于开放组。
微创Ivor-Lewis食管癌切除术创伤较小，恢复时间较短，术后生活质量较好。
