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[左心室肥厚对原发性高血压患者左心室功能的影响。多普勒超声心动图分析]

[Influence of left ventricular hypertrophy on its function in essential arterial hypertension. Analysis by Doppler echocardiography].

作者信息

Vicente Vera T, Díaz de la Vega C, Gabbai F, Andrade Freire A, Pérez de Juan M, Esquivel-Avila J G

机构信息

Instituto Nacional de Cardiología Ignacio Chávez, Tlalpan, México, D.F.

出版信息

Arch Inst Cardiol Mex. 1989 Mar-Apr;59(2):145-53.

PMID:2527486
Abstract

In order to evaluate the influence of left ventricular hypertrophy (LVH) on the function of this ventricle, twenty patients with essential arterial hypertension (EAH) were studied using Doppler echocardiography. Patients with diastolic blood pressure greater than 91 mmHg were included. Antihypertensive treatment was stopped 2 weeks before the study. None of them had any concomitant coronary artery disease nor kidney involvement. Left ventricular diameters, left ventricular mass (LVM), stroke volume, fractional shortening, mean velocity of circumferential shortening (Vcfr), mean velocity of circumferential relaxation, mean velocity of aortic flow and mean E and A velocities of mitral flow as well as the ratio of these velocities (E/A) were measured or calculated. With those values from the entire group, arithmetic means were calculated and the population was divided into two groups: those with values greater than the mean and those with values below the mean for each variable for comparative purposes. The relationship of the individual values was also calculated. The interventricular septum thickness and the left ventricular end diastolic diameter were proportional with diastolic blood pressure (p less than 0.05). The LVM values shown an inverse relationship to the fractional shortening (p less than 0.01), Vcfr (p less than 0.05) as well as end diastolic diameter of left ventricle (r = -0.889, p less than 0.01) and with the stroke volume (r = -0.861, p less than 0.01). The E/A ratio was proportional to the fractional shortening (p less than 0.05) and to Vcfr (r = 0.903). The A velocity of the mitral Doppler flow showed an inverse proportion to the Vcfr (p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为了评估左心室肥厚(LVH)对该心室功能的影响,采用多普勒超声心动图对20例原发性高血压(EAH)患者进行了研究。纳入舒张压大于91 mmHg的患者。研究前2周停用降压治疗。他们均无合并冠状动脉疾病或肾脏受累情况。测量或计算左心室直径、左心室质量(LVM)、每搏输出量、缩短分数、圆周缩短平均速度(Vcfr)、圆周松弛平均速度、主动脉血流平均速度以及二尖瓣血流E和A平均速度及其速度比值(E/A)。根据整个组的这些值计算算术平均值,并将人群分为两组:每个变量值大于平均值的组和值低于平均值的组用于比较。还计算了个体值之间的关系。室间隔厚度和左心室舒张末期直径与舒张压成正比(p<0.05)。LVM值与缩短分数(p<0.01)、Vcfr(p<0.05)以及左心室舒张末期直径(r = -0.889,p<0.01)和每搏输出量(r = -0.861,p<0.01)呈负相关。E/A比值与缩短分数(p<0.05)和Vcfr成正比(r = 0.903)。二尖瓣多普勒血流的A速度与Vcfr呈反比(p<0.05)。(摘要截断于250字)

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