Koc Bora, Bircan Huseyin Yuce, Altaner Semsi, Cinar Ozlem, Ozcelik Umit, Yavuz Alpaslan, Kemik Ozgur
Department of Surgery, Baskent University, Istanbul Research Hospital , Van, Turkey.
Department of Pathology, Baskent University, Istanbul Research Hospital , Van, Turkey.
Infect Dis Rep. 2014 Sep 22;6(3):5512. doi: 10.4081/idr.2014.5512. eCollection 2014 Aug 13.
In recent years, cytomegalovirus (CMV) has been recognized as an important common pathogen in immunocompromized patients. This is due to the increasing number of immunosuppressive medications, intensive cancer chemotherapy use, recurrent transplantations, progressively aging population, and the higher number of human immunodeficiency virus infections. Cytomegalovirus infection especially interests the gastrointestinal tract, anywhere, from the mouth to the anus. Namely, the most commonly affected area is the colon, followed by duodenum, stomach, esophagus and small intestine. The most frequent manifestations of CMV colitis are: diarrhea, fever, gastrointestinal bleeding and abdominal pain. We report here the case of an 82-year-old woman, who was treated for non-Hodgkin lymphoma; she was admitted to the emergency department for abdominal pain and diffuse arthralgia, following massive upper- and lower- gastrointestinal bleeding, due to duodenal and colonic ulcers related to CMV infection.
近年来，巨细胞病毒（CMV）已被公认为免疫功能低下患者的一种重要常见病原体。这是由于免疫抑制药物的使用增加、癌症强化化疗的应用、反复移植、人口老龄化以及人类免疫缺陷病毒感染数量增多所致。巨细胞病毒感染尤其累及胃肠道，从口腔到肛门的任何部位均可受累。也就是说，最常受累的部位是结肠，其次是十二指肠、胃、食管和小肠。CMV结肠炎最常见的表现为：腹泻、发热、胃肠道出血和腹痛。我们在此报告一例82岁女性患者，她因非霍奇金淋巴瘤接受治疗；因与CMV感染相关的十二指肠和结肠溃疡导致上、下消化道大量出血后，因腹痛和弥漫性关节痛入住急诊科。
