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1
The effects of intravenous hydration on amniotic fluid volume and pregnancy outcomes in women with term pregnancy and oligohydramnios: a randomized clinical trial.静脉补液对足月妊娠合并羊水过少孕妇羊水量及妊娠结局的影响：一项随机临床试验。
J Caring Sci. 2012 Aug 25;1(3):123-8. doi: 10.5681/jcs.2012.018. eCollection 2012 Sep.
2
Transabdominal amnioinfusion in preterm premature rupture of membranes.经腹羊膜腔灌注在早产胎膜早破中的应用。
Int J Gynaecol Obstet. 2010 Mar;108(3):199-202. doi: 10.1016/j.ijgo.2009.09.032. Epub 2009 Dec 16.
3
Influence of premature rupture of membrane on the cerebral blood flow in low-birth-weight infant after the delivery.
Brain Dev. 2010 Sep;32(8):631-5. doi: 10.1016/j.braindev.2009.09.023. Epub 2009 Oct 27.
4
Intravenous maternal hydration in third trimester oligohydramnios: effect on amniotic fluid volume.孕晚期羊水过少时静脉补液对母体的影响：对羊水量的作用
J Coll Physicians Surg Pak. 2007 Jun;17(6):336-9.
5
Management of premature rupture of membranes before 25 weeks.25周前胎膜早破的处理
Eur J Obstet Gynecol Reprod Biol. 2007 Apr;131(2):163-8. doi: 10.1016/j.ejogrb.2006.05.016. Epub 2006 Jul 17.
6
Vitamins C and E in the latency period in women with preterm premature rupture of membranes.胎膜早破早产女性潜伏期的维生素C和维生素E
Int J Gynaecol Obstet. 2005 Jul;90(1):16-20. doi: 10.1016/j.ijgo.2005.03.023.
7
Maternal and fetal outcomes of spontaneous preterm premature rupture of membranes.胎膜自然早产胎膜早破的母儿结局
J Am Osteopath Assoc. 2004 Dec;104(12):537-42.
8
Alteration of the amniotic fluid and neonatal outcome.羊水的改变与新生儿结局。
Acta Biomed. 2004;75 Suppl 1:71-5.
9
Duration of the increase in amniotic fluid index (AFI) after acute maternal hydration.急性母体补液后羊水指数（AFI）升高的持续时间。
Arch Gynecol Obstet. 2004 Mar;269(3):173-5. doi: 10.1007/s00404-002-0346-z. Epub 2003 Oct 24.
10
Preterm premature rupture of membranes and neonatal outcome prior to 34 weeks of gestation.妊娠34周前胎膜早破与新生儿结局
Int J Gynaecol Obstet. 2003 Aug;82(2):167-72. doi: 10.1016/s0020-7292(03)00125-5.

静脉补液对胎膜早破孕妇羊水指数的影响：一项随机临床试验

The Effects of Intravenous Hydration on Amniotic Fluid Index in Pregnant Women with Preterm premature Rupture of Membranes: A Randomized Clinical Trial.

作者信息

Shahnazi Mahnaz, Tagavi Simin, Hajizadeh Khadije, Farshbaf Khalili Azize

机构信息

Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.

Department of Obstetrics, Gynecology and Reproductive Sciences, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

J Caring Sci. 2013 Feb 26;2(1):47-52. doi: 10.5681/jcs.2013.006. eCollection 2013 Mar.

DOI:10.5681/jcs.2013.006
PMID:25276709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4161108/
Abstract

INTRODUCTION

Preterm premature rupture of membranes (PPROM) can result in fetal complications such as oligohydramnios. This study aimed to determine the effects of intravenous (IV) fluid bolus on amniotic fluid index (AFI) in pregnant women with PPROM.

METHODS

24 women with PPROM during singleton live pregnancy of 28 to 34 weeks whose baseline AFI was ≤ 5cm were randomized into two groups. The study group received one liter intravenous fluid bolus of isotonic Ringer serum during 30-minute period. Reevaluations of amniotic fluid index in both groups were made 90 minutes and 48 hours after baseline measurement. Independent t-test and paired t-test were used to compare the two groups and mean amniotic fluid index before and after treatment, respectively.

RESULTS

The results of this study demonstrate that AFI decreased statistically significant in both the control and study groups. AFI decreased in both groups at 48 hours later. This decrease was not statistically significant in any group. The mean change in AFI (90 minutes and baseline) and (48 hours and baseline) between the two groups were not significant. The time between mean baseline measurements and delivery were 196.41 and 140.58 hours in the study and control groups, respectively. This difference was not statistically significant.

CONCLUSION

This study did not find significant impact of hydration On AFI as a prophylactic method on oligohydramnios in pregnant women with PPROM.

摘要

引言

胎膜早破（PPROM）可导致胎儿并发症，如羊水过少。本研究旨在确定静脉推注液体对PPROM孕妇羊水指数（AFI）的影响。

方法

24名单胎活产、孕周为28至34周且基线AFI≤5cm的PPROM孕妇被随机分为两组。研究组在30分钟内接受1升等渗林格氏液静脉推注。两组在基线测量后90分钟和48小时重新评估羊水指数。分别使用独立t检验和配对t检验比较两组以及治疗前后的平均羊水指数。

结果

本研究结果表明，对照组和研究组的AFI均有统计学意义的下降。两组在48小时后AFI均下降。但在任何一组中，这种下降均无统计学意义。两组之间AFI（90分钟与基线）和（48小时与基线）的平均变化无显著差异。研究组和对照组从平均基线测量到分娩的时间分别为196.41小时和140.58小时。这种差异无统计学意义。

结论

本研究未发现补液作为预防PPROM孕妇羊水过少的方法对AFI有显著影响。