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亨廷顿舞蹈病中的体感诱发电位——配对刺激研究

Somatosensory evoked potentials in Huntington's disease--studies with paired stimulation.

作者信息

Kanda F, Jinnai K, Takahashi K, Abe H, Yasuda M, Tada K, Fujita T

出版信息

Electromyogr Clin Neurophysiol. 1989 Jul-Aug;29(5):287-91.

PMID:2527738
Abstract

The somatosensory evoked potentials (SEPs) and recovery functions of the SEP with paired stimulation were studied in patients with Huntington's disease (HD). A significant decrease in amplitude of the SEP was observed in 4 of the 5 patients. In addition, with paired stimulation, the second SEP amplitudes were normalized at intervals of about 10 ms. These findings possibly suggest that functional block rather than organic change in the thalamus may play an important role in the reduction in SEP amplitude in HD.

摘要

对亨廷顿舞蹈病(HD)患者的体感诱发电位(SEP)及配对刺激下SEP的恢复功能进行了研究。5例患者中有4例观察到SEP波幅显著降低。此外,在配对刺激时,第二个SEP波幅在约10毫秒的间隔时恢复正常。这些发现可能提示,丘脑的功能阻滞而非器质性改变可能在HD患者SEP波幅降低中起重要作用。

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