Wagner Glenn J, Goggin Kathy, Mindry Deborah, Beyeza-Kashesya Jolly, Finocchario-Kessler Sarah, Woldetsadik Mahlet Atakilt, Khanakwa Sarah, Wanyenze Rhoda K
RAND Corporation, 1776 Main St., Santa Monica, CA, 90407, USA,
AIDS Behav. 2015 Jun;19(6):1078-88. doi: 10.1007/s10461-014-0906-9.
We examined the correlates of use of safer conception methods (SCM) in a sample of 400 Ugandan HIV clients (75 % female; 61 % on antiretroviral therapy; 61 % with HIV-negative or unknown status partners) in heterosexual relationships with fertility intentions. SCM assessed included timed unprotected intercourse, manual self-insemination, sperm washing, and pre-exposure prophylaxis (PrEP). In the 6 months prior to baseline, 47 (12 %) reported using timed unprotected intercourse to reduce risk of HIV infection (or re-infection), none had used manual self-insemination or sperm washing, and two had used PrEP. In multiple regression analysis, correlates of use of timed unprotected intercourse included greater perceptions of partner's willingness to use SCM and providers' stigma of childbearing among people living with HIV, higher SCM knowledge, and desire for a child within the next 6 months. These findings highlight the need for policy and provider training regarding integration of couples' safer conception counselling into HIV care.
我们在400名有生育意愿的乌干达异性恋HIV感染者样本中（75%为女性；61%接受抗逆转录病毒治疗；61%的性伴侣为HIV阴性或感染状况不明），研究了使用更安全受孕方法（SCM）的相关因素。评估的SCM包括定时无保护性交、手动自我授精、精子洗涤和暴露前预防（PrEP）。在基线前的6个月里，47人（12%）报告使用定时无保护性交来降低HIV感染（或再感染）风险，无人使用手动自我授精或精子洗涤，两人使用了PrEP。在多元回归分析中，使用定时无保护性交的相关因素包括：对伴侣使用SCM意愿的更高认知、HIV感染者中医疗服务提供者对生育的污名化、更高的SCM知识水平，以及在未来6个月内生育子女的愿望。这些发现凸显了将夫妻更安全受孕咨询纳入HIV护理的政策和医疗服务提供者培训的必要性。
