Matsuda M, Nagao K, Baba K, Nishimura R, Matsuoka Y, Ueno Y, Morinaga H, Nagase H, Kawano H
Dept. of Surgery (Coloproctology), Kumamoto Municipal Hospital.
Gan To Kagaku Ryoho. 1989 Aug;16(8 Pt 1):2659-62.
A 68-year-old male, who had advanced rectal cancer with multiple pulmonary metastases, had undergone resection of rectal cancer operatively and was treated with a combination chemotherapy using 5'-DFUR (5'-deoxy-5-fluorouridine) and MMC (mitomycin C) for multiple pulmonary metastases. Nine months from the start of this therapy, pulmonary metastatic lesions disappeared completely on chest X-ray examination and computed tomography. This case corresponded to complete response (CR) according to the response criteria proposed by Koyama-Saitoh. No significant side effects were observed during this chemotherapy. From the results in this case, the combination chemotherapy was considered to be one of the effective antineoplastic therapies available for pulmonary metastasis from large bowel cancer.
一名68岁男性，患有晚期直肠癌并伴有多发肺转移，已接受直肠癌手术切除，并使用5'-去氧-5-氟尿苷（5'-DFUR）和丝裂霉素C（MMC）联合化疗治疗多发肺转移。从该治疗开始9个月后，胸部X线检查和计算机断层扫描显示肺转移病灶完全消失。根据小山-斋藤提出的反应标准，该病例符合完全缓解（CR）。在此次化疗期间未观察到明显的副作用。从该病例的结果来看，联合化疗被认为是可用于治疗大肠癌肺转移的有效抗肿瘤治疗方法之一。
