Kalaga A, Addy M, Hunter B
Department of Child Dental Health, Dental School, University of Wales College of Medicine, Cardiff, United Kingdom.
J Periodontol. 1989 Jul;60(7):381-5. doi: 10.1902/jop.1989.60.7.381.
Chlorhexidine has been used as an aid to or replacement for oral hygiene measures in special needs groups such as the handicapped. Previous studies have indicated that spray delivery of chlorhexidine is both effective and acceptable. This study evaluated twice daily use of a 0.2% chlorhexidine spray as an adjunct to toothbrushing in a group of physically and mentally handicapped adults attending a day training center. The study was a double-blind, placebo controlled, cross-over design involving two 31 days regimens separated by 30 days. Plaque, bleeding on probing, and pocketing were measured at the beginning and end of each regimen. There were clinically and statistically significantly lower plaque and bleeding scores at the end of the chlorhexidine compared to the placebo period. Pocketing was also significantly less after chlorhexidine, although in clinical terms the difference was small. The apparent acceptability and effectiveness of the regimen suggests that small doses of chlorhexidine delivered by sprays may be of considerable value as an aid to oral hygiene in handicapped individuals.
洗必泰已被用作特殊需求群体(如残疾人)口腔卫生措施的辅助手段或替代品。先前的研究表明,洗必泰喷雾给药既有效又可接受。本研究评估了在一所日间培训中心的一组身体和智力有缺陷的成年人中,每天两次使用0.2%洗必泰喷雾作为刷牙辅助手段的效果。该研究采用双盲、安慰剂对照、交叉设计,包括两个31天的疗程,中间间隔30天。在每个疗程开始和结束时测量菌斑、探诊出血和牙周袋深度。与安慰剂期相比,洗必泰疗程结束时菌斑和出血评分在临床和统计学上均显著降低。洗必泰治疗后牙周袋深度也显著减小,尽管从临床角度来看差异较小。该治疗方案明显的可接受性和有效性表明,喷雾给药的小剂量洗必泰作为残疾人口腔卫生辅助手段可能具有相当大的价值。