Bonaparte James P, Ellis David E
Department of Otolaryngology-Head and Neck Surgery, University of Ottawa, Ottawa, Ontario, Canada; and Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology, University of Toronto, Toronto, Ontario, Canada.
Plast Reconstr Surg Glob Open. 2014 Jun 6;2(5):e159. doi: 10.1097/GOX.0000000000000106. eCollection 2014 May.
Treatments for cosmetically unpleasing periocular and lateral temporal veins are limited. The purpose of this study was to test the hypothesis that the application of topical lidocaine before the cosmetic treatment of periorbital and lateral temporal veins with a neodymium-doped yttrium aluminum garnet (ND:YAG) laser will result in a significant reduction in subjective pain compared with placebo as assessed using a visual analogue scale.
Twenty patients who required bilateral treatment of facial veins were randomly assigned to receive either placebo or 30% lidocaine gel applied topically over the veins, a split-body design. Both the investigator and the patient were blinded to the treatment. An ND:YAG laser was used to treat the veins. Patients completed a visual analogue scale to assess the pain on each side of the face. Data were analyzed using nonparametric data testing.
There was a 64.0% reduction in pain on the treatment side compared with the placebo side (P < 0.001). There was no significant difference in patient-assessed subjective efficacy between sides (P = 0.2). Complications were minimal and mild.
Patients undergoing periorbital and temporal vein ablation using ND:YAG laser should be offered topical lidocaine as the pain levels are moderate. The use of topical 30% lidocaine results in a significant reduction in pain levels.
对于外观不佳的眶周静脉和颞侧静脉，治疗方法有限。本研究的目的是验证以下假设：与使用视觉模拟量表评估的安慰剂相比，在使用掺钕钇铝石榴石（ND:YAG）激光对眶周静脉和颞侧静脉进行美容治疗前应用局部利多卡因，将使主观疼痛显著减轻。
20例需要对面部静脉进行双侧治疗的患者被随机分配接受安慰剂或在静脉上局部应用30%利多卡因凝胶，采用自身对照设计。研究者和患者均对治疗不知情。使用ND:YAG激光治疗静脉。患者完成视觉模拟量表以评估面部两侧的疼痛。使用非参数数据检验分析数据。
与安慰剂侧相比，治疗侧疼痛减轻了64.0%（P < 0.001）。两侧患者评估的主观疗效无显著差异（P = 0.2）。并发症轻微且少见。
由于疼痛程度为中度，接受使用ND:YAG激光进行眶周和颞静脉消融的患者应使用局部利多卡因。局部应用30%利多卡因可显著降低疼痛程度。
