非洲爪蟾变态发育过程中免疫系统的变化。
Changes in the immune system during metamorphosis of Xenopus.
作者信息
Flajnik M F, Hsu E, Kaufman J F, Pasquier L D
出版信息
Immunol Today. 1987;8(2):58-64. doi: 10.1016/0167-5699(87)90240-4.
PMID:25291685
Abstract
Profound immunological changes occur as tadpoles metamorphose into adult amphibians. These include the expression of a different antibody repertoire, a lessening of skin graft tolerance, the appearance on leukocytes of class I MHC antigens. Here Martin Flajnik and his colleagues review what is known of these changes in Xenopus and speculate on how they may occur.
摘要
当蝌蚪变态发育为成年两栖动物时，会发生深刻的免疫变化。这些变化包括不同抗体库的表达、皮肤移植耐受性的降低、I类主要组织相容性复合体（MHC）抗原在白细胞上的出现。在此，马丁·弗拉伊尼克及其同事回顾了非洲爪蟾中这些变化的已知情况，并推测了它们可能的发生方式。
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