Iavich M P, Rozhitskaia I I, Golubeva L Iu, Meerson F Z
Patol Fiziol Eksp Ter. 1989 May-Jun(3):39-42.
In modelling compensatory hyperfunction of the heart (CHH) due to coarctation of the aorta, the replication rate in the nuclei of myocardial cells increases in 24 hours and becomes 20 fold the control values in 48 hours. The replication rate in myocardial mitochondria in CHH reduces at the beginning of hyperfunction but increases almost two fold in 48 hours. The DNA reparation rate in the nuclei of the myocardial cells does not change in CHH. The rate of this process, however, increases significantly (by 50-74%) in cardiac cells of animals subjected to operation but without coarctation of the aorta.
在对因主动脉缩窄导致的心脏代偿性高功能（CHH）进行建模时，心肌细胞核中的复制率在24小时内增加，并在48小时时达到对照值的20倍。CHH中心肌线粒体的复制率在高功能开始时降低，但在48小时内几乎增加两倍。CHH中心肌细胞核中的DNA修复率没有变化。然而，在接受手术但没有主动脉缩窄的动物的心脏细胞中，这一过程的速率显著增加（50%-74%）。
