Geraldo Reinaldo Barros, Sathler Plínio Cunha, Lourenço André Luiz, Saito Max Seidy, Cabral Lucio M, Rampelotto Pabulo Henrique, Castro Helena Carla
Programa de Pós-graduação em Ciências e Biotecnologia, Instituto de Biologia, Universidade Federal Fluminense (UFF), Niterói CEP 24210-130, RJ, Brazil.
Programa de Pós-graduação em Patologia, Departamento de Patologia, Hospital Universitário Antônio Pedro (HUAP), Universidade Federal Fluminense (UFF), Niterói CEP 24030-215, RJ, Brazil.
Int J Mol Sci. 2014 Oct 7;15(10):17901-19. doi: 10.3390/ijms151017901.
Platelets are cytoplasmatic fragments from bone marrow megakaryocytes present in blood. In this work, we review the basis of platelet mechanisms, their participation in syndromes and in arterial thrombosis, and their potential as a target for designing new antithrombotic agents. The option of new biotechnological sources is also explored.
血小板是血液中存在的骨髓巨核细胞的细胞质碎片。在这项工作中，我们综述了血小板机制的基础、它们在综合征和动脉血栓形成中的作用，以及它们作为设计新型抗血栓药物靶点的潜力。同时也探讨了新的生物技术来源的选择。
