Rigid Solutions, LLC , Shelbyville, Kentucky 40066, United States.
Org Lett. 2014 Oct 17;16(20):5238-41. doi: 10.1021/ol501418t. Epub 2014 Oct 8.
The conventional chemical reaction workup based on liquid-liquid extraction is a time- and labor-consuming practice. We have developed a substantially faster technique for the routine workup that relies on a porous organic polymer (Porelite) supported solvent phase to extract organic products from an aqueous reaction mixture. We call this process rigid solvent extraction. Using this technique, the tedious liquid-liquid extraction can be replaced by a simple filtration, making parallel operation and automation feasible.
传统的基于液-液萃取的化学反应后处理是一项耗时耗力的操作。我们开发了一种更快的常规后处理技术,该技术依赖于多孔有机聚合物(Porelite)支撑的溶剂相从水相反应混合物中萃取有机产物。我们称此过程为刚性溶剂萃取。使用该技术,可以通过简单的过滤代替繁琐的液-液萃取,从而实现并行操作和自动化。