Salehi Leila, Azmi Reza
Department of Computer Engineering, Alzahra University, Tehran, Iran.
J Med Signals Sens. 2014 Jul;4(3):202-10.
Breast cancer continues to be a significant public health problem in the world. Early detection is the key for improving breast cancer prognosis. In this way, magnetic resonance imaging (MRI) is emerging as a powerful tool for the detection of breast cancer. Breast MRI presently has two major challenges. First, its specificity is relatively poor, and it detects many false positives (FPs). Second, the method involves acquiring several high-resolution image volumes before, during, and after the injection of a contrast agent. The large volume of data makes the task of interpretation by the radiologist both complex and time-consuming. These challenges have led to the development of the computer-aided detection systems to improve the efficiency and accuracy of the interpretation process. Detection of suspicious regions of interests (ROIs) is a critical preprocessing step in dynamic contrast-enhanced (DCE)-MRI data evaluation. In this regard, this paper introduces a new automatic method to detect the suspicious ROIs for breast DCE-MRI based on region growing. The results indicate that the proposed method is thoroughly able to identify suspicious regions (accuracy of 75.39 ± 3.37 on PIDER breast MRI dataset). Furthermore, the FP per image in this method is averagely 7.92, which shows considerable improvement comparing to other methods like ROI hunter.
乳腺癌仍然是全球一个重大的公共卫生问题。早期检测是改善乳腺癌预后的关键。通过这种方式,磁共振成像(MRI)正成为检测乳腺癌的有力工具。目前,乳腺MRI面临两大挑战。其一,其特异性相对较差,会检测出许多假阳性(FP)。其二,该方法需要在注射造影剂之前、期间和之后采集多个高分辨率图像容积。大量的数据使得放射科医生的解读任务既复杂又耗时。这些挑战促使了计算机辅助检测系统的发展,以提高解读过程的效率和准确性。在动态对比增强(DCE)-MRI数据评估中,检测可疑的感兴趣区域(ROI)是一个关键的预处理步骤。在这方面,本文介绍了一种基于区域生长的自动检测乳腺DCE-MRI可疑ROI的新方法。结果表明,所提出的方法能够完全识别可疑区域(在PIDER乳腺MRI数据集上的准确率为75.39±3.37)。此外,该方法每张图像的平均假阳性为7.92,与ROI hunter等其他方法相比有显著改进。