Baker Brian J, Poonja Shameer, Mesrobian Myrna, Lai Anna, Hwang Steven
MMWR Morb Mortal Wkly Rep. 2014 Oct 10;63(40):907-8.
In early 2013, the Los Angeles County Department of Public Health learned of two patients diagnosed with tuberculosis (TB) who had received care at the same outpatient health care facility (facility A). Facility A is a center for infusions of chemotherapeutic and biologic agents and serves a large number of immunocompromised persons who were potentially exposed to infectious TB. If infected, immunocompromised persons are at elevated risk for progression to TB disease. The two patients (patient A and patient B) both had pulmonary TB, with acid-fast bacilli found on sputum-smear microscopy, and had visited facility A multiple times during their infectious periods. Despite initial concerns that these two cases could be the result of person-to-person transmission at facility A, genotyping of the Mycobacterium tuberculosis isolates from these two patients showed that they were infected with unrelated strains.
2013年初，洛杉矶县公共卫生部获悉，有两名被诊断患有结核病（TB）的患者曾在同一家门诊医疗设施（设施A）接受治疗。设施A是一家输注化疗药物和生物制剂的中心，为大量可能接触传染性结核病的免疫功能低下者提供服务。免疫功能低下者一旦感染，发展为结核病的风险会升高。这两名患者（患者A和患者B）均患有肺结核，痰涂片显微镜检查发现抗酸杆菌，且在传染期多次前往设施A。尽管最初担心这两例病例可能是设施A内人际传播的结果，但对这两名患者结核分枝杆菌分离株的基因分型显示，他们感染的是不相关的菌株。
