Stone Danielle, McCabe Patricia, Palme Carsten E, Heard Robert, Eastwood Clare, Riffat Faruque, Madill Catherine
Voice Research Laboratory, Discipline of Speech Pathology, Faculty of Health Sciences, The University of Sydney, Lidcombe, New South Wales, Australia; Crown Princess Mary Cancer Care Centre, Westmead Hospital, Sydney, New South Wales, Australia; Department of Speech Pathology, Westmead Hospital, Sydney, New South Wales, Australia.
Voice Research Laboratory, Discipline of Speech Pathology, Faculty of Health Sciences, The University of Sydney, Lidcombe, New South Wales, Australia.
J Voice. 2015 May;29(3):370-81. doi: 10.1016/j.jvoice.2014.08.018. Epub 2014 Oct 7.
OBJECTIVES/HYPOTHESES: This study proposed the use of signal typing and acoustic measures experimentally validated for aperiodic voices to investigate voice outcomes after transoral laser microsurgery (TLM) for early glottic carcinoma. It was of interest whether signal type and pitch-tracking indicators would reveal unreliable perturbation and noise measures. As an alternative, smoothed cepstral peak prominence (CPPS) was used for the first time in this population.
A descriptive study of patients treated with TLM for early glottic carcinoma.
All participants (n=14) performed a series of vocal tasks. Narrowband spectrograms were generated from voice recordings and classified into one of four signal types. The perturbation and noise measures of periodic or near-periodic signals only were reported. The CPPS for sustained vowel (CPPS-/a/) and connected speech (CPPS-s) were calculated for all participants. The relationship between voice outcomes and tumor and TLM factors was investigated.
Nine of 14 participants had an aperiodic type 3 signal. Three of 14 participants had voices considered reliable for perturbation analysis. Absolute jitter, %jitter, %shimmer, and signal-to-noise ratio were all low; however, CPPS-/a/ and CPPS-s amplitudes were below the normal range for most participants. Involvement of the anterior commissure, number of TLM episodes, and time post-surgery were associated with worse voice outcomes. There were strong correlations between signal type, CPPS-/a/, and pitch-tracking indicators.
The limitations of perturbation analysis should be considered when analyzing the voice after TLM. Signal type should be considered before conducting perturbation analysis. The CPPS-/a/ and CPPS-s may be more reliable acoustic outcome measures for this population.
目的/假设：本研究提议使用经实验验证适用于非周期性嗓音的信号分型和声学测量方法，来研究早期声门癌经口激光显微手术（TLM）后的嗓音结果。信号类型和音高跟踪指标是否会揭示不可靠的扰动和噪声测量结果，这一点令人关注。作为一种替代方法，本研究首次在该人群中使用了平滑谐波峰值突出度（CPPS）。
对接受TLM治疗的早期声门癌患者进行的描述性研究。
所有参与者（n = 14）执行了一系列发声任务。从语音记录中生成窄带频谱图，并将其分类为四种信号类型之一。仅报告周期性或近周期性信号的扰动和噪声测量结果。计算了所有参与者持续元音（CPPS-/a/）和连贯语音（CPPS-s）的CPPS。研究了嗓音结果与肿瘤及TLM因素之间的关系。
14名参与者中有9名具有非周期性3型信号。14名参与者中有3名的嗓音被认为可用于扰动分析。绝对抖动、%抖动、%闪烁和信噪比均较低；然而，大多数参与者的CPPS-/a/和CPPS-s幅度低于正常范围。前联合受累、TLM发作次数和术后时间与较差的嗓音结果相关。信号类型、CPPS-/a/和音高跟踪指标之间存在强相关性。
在分析TLM后的嗓音时，应考虑扰动分析的局限性。在进行扰动分析之前应考虑信号类型。对于该人群，CPPS-/a/和CPPS-s可能是更可靠的声学结果测量指标。
