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绝经后非裔美国女性的小梁骨评分(TBS)

Trabecular bone score (TBS) in postmenopausal African American women.

作者信息

Aloia J F, Mikhail M, Usera G, Dhaliwal R, Islam S

机构信息

Winthrop University Hospital, 222 Station Plaza North, Suite 510, Mineola, NY, 11501-3893, USA,

出版信息

Osteoporos Int. 2015 Mar;26(3):1155-61. doi: 10.1007/s00198-014-2928-6. Epub 2014 Oct 11.

Abstract

UNLABELLED

Trabecular bone score (TBS) is a newly developed parameter that can be derived from DXA scans of the spine and may reflect bone quality. This study provides TBS values in healthy postmenopausal women of African descent.

INTRODUCTION

African American women have a lower risk for osteoporotic fractures as a result of higher bone density and better bone quality. We examined TBS in postmenopausal African American women since there are no previous reports in this population.

METHODS

This was a study of healthy African American volunteers using baseline values prior to their participation in two vitamin D intervention studies conducted at an ambulatory research center of an academic health center.

RESULTS

The study population consisted of 518 healthy postmenopausal African American women with a mean age of 66 years and a BMI of 30.1. Mean TBS (L1 to L4) was 1.300(.100 SD). Significant negative correlations were found between TBS and age and BMI. None of the biochemical variables were significantly correlated with TBS whereas the various bone density sites were correlated with TBS.

CONCLUSION

TBS values for African American women are higher than those reported in the literature for white women and are inversely related to age and BMI.

摘要

未标注

小梁骨评分(TBS)是一种新开发的参数,可从脊柱的双能X线吸收测定(DXA)扫描中得出,可能反映骨质量。本研究提供了非洲裔健康绝经后女性的TBS值。

引言

非裔美国女性由于骨密度较高和骨质量较好,骨质疏松性骨折的风险较低。由于此前该人群尚无相关报道,我们对绝经后非裔美国女性的小梁骨评分进行了研究。

方法

这是一项针对健康非裔美国志愿者的研究,使用她们在参与学术健康中心门诊研究中心进行的两项维生素D干预研究之前的基线值。

结果

研究人群包括518名健康绝经后非裔美国女性,平均年龄66岁,体重指数为30.1。平均TBS(L1至L4)为1.300(标准差0.100)。发现TBS与年龄和体重指数之间存在显著负相关。生化变量均与TBS无显著相关性,而不同的骨密度部位与TBS相关。

结论

非裔美国女性的TBS值高于文献报道的白人女性,且与年龄和体重指数呈负相关。

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