Carlino Elisa, Piedimonte Alessandro, Frisaldi Elisa
Neuroscience Department and National Institute of Neuroscience Labs, University of Turin Medical School, Corso Raffaello 30, 10125, Torino, Italy,
Handb Exp Pharmacol. 2014;225:149-57. doi: 10.1007/978-3-662-44519-8_9.
In this chapter we present and discuss recent studies on the mechanisms underlying placebo and nocebo effects in physical performance, showing how expectations and both pharmacological and nonpharmacological preconditioning procedures can be very effective in inducing placebo responses, with important implications for sport competitions. Furthermore, we place these findings within the biological model of central governor of fatigue, whose main goal is to protect our body from damage. A crucial aspect of this emerging field of placebo studies is related to the limit beyond which these procedures can be called doping in all respects.
在本章中,我们展示并讨论了关于身体机能中安慰剂和反安慰剂效应潜在机制的最新研究,揭示了期望以及药理学和非药理学预处理程序如何能够非常有效地诱发安慰剂反应,这对体育竞赛具有重要意义。此外,我们将这些发现置于疲劳中枢调控器的生物学模型中,其主要目标是保护我们的身体免受损伤。安慰剂研究这一新兴领域的一个关键方面与一个界限相关,超过这个界限,这些程序在各方面都可被称为使用兴奋剂。