Winokur Ronald S, Du Jerry Y, Pua Bradley B, Talenfeld Adam D, Sista Akhilesh K, Schiffman Marc A, Trost David W, Madoff David C
Department of Radiology, Division of Interventional Radiology, New York-Presbyterian Hospital/Weill Cornell Medical Center, 525 E. 68th St., P-518, New York, NY 10065.
Department of Radiology, Division of Interventional Radiology, New York-Presbyterian Hospital/Weill Cornell Medical Center, 525 E. 68th St., P-518, New York, NY 10065.
J Vasc Interv Radiol. 2014 Dec;25(12):1939-1946.e1. doi: 10.1016/j.jvir.2014.08.014. Epub 2014 Oct 11.
To analyze in vivo ablation properties of microwave ablation antennae in tumor-bearing human livers by performing retrospective analysis of ablation zones following treatment with two microwave ablation systems.
Percutaneous microwave ablations performed in the liver between February 2011 and February 2013 with use of the AMICA and Certus PR ablation antennae were included. Immediate postablation computed tomography images were evaluated retrospectively for ablation length, diameter, and volume. Ablation length, diameter, and volume indices were calculated and compared between in vivo results and references provided from each device manufacturer. The two microwave antenna models were then also compared versus each other.
Twenty-five ablations were performed in 20 patients with the AMICA antenna, and 11 ablations were performed in eight patients with the Certus PR antenna. The AMICA and Certus PR antennae showed significant differences in ablation length (P = .013 and P = .009), diameter (P = .001 and P = .009), and volume (P = .003 and P = .009). The AMICA ablation indices were significantly higher than the Certus PR ablation indices in length (P = .026) and volume (P = .002), but there was no significant difference in ablation diameter indices (P = .110).
In vivo ablation indices of human tumors are significantly smaller than reference ex vivo ablation indices, and there are significant differences in ablation indices and sphericity between devices.
通过对使用两种微波消融系统治疗后的消融区域进行回顾性分析，来分析微波消融天线在荷瘤人体肝脏中的体内消融特性。
纳入2011年2月至2013年2月期间使用AMICA和Certus PR消融天线在肝脏中进行的经皮微波消融。对消融后即刻的计算机断层扫描图像进行回顾性评估，以确定消融长度、直径和体积。计算消融长度、直径和体积指数，并将体内结果与各设备制造商提供的参考值进行比较。然后还对两种微波天线模型进行了相互比较。
使用AMICA天线对20例患者进行了25次消融，使用Certus PR天线对8例患者进行了11次消融。AMICA和Certus PR天线在消融长度（P = 0.013和P = 0.009）、直径（P = 0.001和P = 0.009）和体积（P = 0.003和P = 0.009）方面存在显著差异。AMICA消融指数在长度（P = 0.026）和体积（P = 0.002）方面显著高于Certus PR消融指数，但在消融直径指数方面无显著差异（P = 0.110）。
人体肿瘤的体内消融指数显著小于参考离体消融指数，并且不同设备之间的消融指数和球度存在显著差异。
