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通过癌症中心的并发症回顾评估介入性支气管镜检查的安全性

Safety of interventional bronchoscopy through complication review at a cancer center.

作者信息

Hsu Li-Han, Liu Chia-Chuan, Ko Jen-Sheng, Chen Chao-Chun, Feng An-Chen

机构信息

Department of Medicine, National Yang-Ming University Medical School, Taipei, Taiwan.

Division of Pulmonary and Critical Care Medicine, Sun Yat-Sen Cancer Center, Taipei, Taiwan.

出版信息

Clin Respir J. 2016 May;10(3):359-67. doi: 10.1111/crj.12225. Epub 2014 Nov 3.

Abstract

BACKGROUND AND AIMS

There have been rapid advances in the area of interventional bronchoscopy over the past 15 years, but associated complications have been rarely discussed. A longitudinal evaluation of the same operator's performance at a cancer center is reported.

METHODS

A detailed record review of diagnostic and therapeutic bronchoscopy between January 1997 and March 2013 was conducted.

RESULTS

Among the 1358 diagnostic bronchoscopies, there were nine major complications requiring premature termination and three pneumothoraces found during follow-up (0.88%). An escalation in the level of care was required for four patients with massive bleeding, asthma attack, sedation intoxication and myocardial ischemia, respectively. Six cases occurred after brushing (0.71%), and five cases before any sampling procedure was conducted. The complication rate was highest for peripheral lesions (1.03%). Among the 109 therapeutic bronchoscopies, no major patient-specific complication occurred except for excessive granulation tissue formation following metallic stenting in one patient with benign tracheal stenosis.

CONCLUSION

The complication rate with regard to bronchoscopy is comparable with historical controls according to the related literature, and their occurrence appears to be sporadic, not relevant to patient characteristics and mostly related to the bronchoscopy itself rather than the introduction of new techniques. Bronchoscopy remains safe along with technical innovations. However, risk recognition and effective prevention is essential.

摘要

背景与目的

在过去15年中,介入性支气管镜检查领域取得了快速进展,但相关并发症却很少被讨论。本文报告了对某癌症中心同一操作者的表现进行的纵向评估。

方法

对1997年1月至2013年3月期间的诊断性和治疗性支气管镜检查记录进行了详细回顾。

结果

在1358例诊断性支气管镜检查中,有9例出现严重并发症,需要提前终止检查,随访期间发现3例气胸(0.88%)。分别有4例患者因大出血、哮喘发作、镇静剂中毒和心肌缺血需要提高护理级别。6例并发症发生在刷检后(0.71%),5例发生在任何采样操作之前。外周病变的并发症发生率最高(1.03%)。在109例治疗性支气管镜检查中,除1例良性气管狭窄患者在金属支架置入后出现过度肉芽组织形成外,未发生严重的特定患者并发症。

结论

根据相关文献,支气管镜检查的并发症发生率与历史对照相当,其发生似乎是散发性的,与患者特征无关,主要与支气管镜检查本身有关,而非新技术的引入。随着技术创新,支气管镜检查仍然是安全的。然而,风险识别和有效预防至关重要。

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