Auclair C A
JOGN Nurs. 1979 Jan-Feb;8(1):35-9. doi: 10.1111/j.1552-6909.1979.tb00795.x.
Exposure to the drug diethylstilbestrol (DES) during the first 18 weeks of prenatal life can have many results ranging from benign misconfigurations of the reproductive organs to adenocarcinoma. Since the drug was routinely administered to pregnant American women from 1940 to 1970, a large population of Americans are involved. The key factor is early awareness to the exposure and careful follow-up. Since many of those exposed are unaware that they received DES, the health care profession must be attuned to the signs and symptoms predisposed by the exposure and be able to provide adequate follow-up and education concerning this medical problem.
在孕期的前18周接触己烯雌酚（DES）药物可能会产生许多后果，从生殖器官的良性畸形到腺癌不等。由于该药物在1940年至1970年间被常规用于美国孕妇，涉及大量美国人。关键因素是对接触情况的早期认知和仔细的随访。由于许多接触者并未意识到自己接触过DES，医疗保健行业必须留意接触所引发的体征和症状，并能够就这一医疗问题提供充分的随访和教育。
