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淋巴结切除术在卵巢癌治疗中的作用。

Role of lymphadenectomy for ovarian cancer.

作者信息

Mikami Mikio

机构信息

Department of Obstetrics and Gynecology, Tokai University School of Medicine, Isehara, Japan.

出版信息

J Gynecol Oncol. 2014 Oct;25(4):279-81. doi: 10.3802/jgo.2014.25.4.279.

DOI:10.3802/jgo.2014.25.4.279
PMID:25310033
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4195296/
Abstract

Japan Society of Gynecologic Oncology (JSGO) recently revised its Ovarian Cancer Treatment Guidelines and the 4th edition will be released next year. This Guidelines state that lymphadenectomy is essential to allow accurate assessment of the clinical stage in early ovarian cancer, but there is no randomized controlled trial that shows any therapeutic efficacy of lymphadenectomy. In patients with advanced stage tumors, lymphadenectomy should be considered if optimal debulking has been performed. I fully agree with this recommendation of the JSGO and I would like to discuss the role of lymphadenectomy in the management of ovarian cancer.

摘要

日本妇科肿瘤学会（JSGO）最近修订了其卵巢癌治疗指南，第四版将于明年发布。该指南指出，淋巴结切除术对于准确评估早期卵巢癌的临床分期至关重要，但尚无随机对照试验表明淋巴结切除术具有任何治疗效果。对于晚期肿瘤患者，如果已进行了最佳肿瘤细胞减灭术，则应考虑进行淋巴结切除术。我完全同意JSGO的这一建议，并且想讨论一下淋巴结切除术在卵巢癌治疗中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa81/4195296/fb98a8325efd/jgo-25-279-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa81/4195296/fb98a8325efd/jgo-25-279-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa81/4195296/fb98a8325efd/jgo-25-279-g001.jpg

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本文引用的文献

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Lymph node metastasis in grossly apparent stages I and II epithelial ovarian cancer.大体可见Ⅰ期和Ⅱ期上皮性卵巢癌的淋巴结转移。
Int J Gynecol Cancer. 2010 Apr;20(3):341-5. doi: 10.1111/IGC.0b013e3181cf6271.
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Potential role of lymphadenectomy in advanced ovarian cancer: a combined exploratory analysis of three prospectively randomized phase III multicenter trials.淋巴结切除术在晚期卵巢癌中的潜在作用：三项前瞻性随机 III 期多中心试验的联合探索性分析。
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Impact of Lymph Node Sampling in Stage II and III Epithelial Ovarian Cancer Patients with Clinically Negative Lymph Nodes.淋巴结采样对临床淋巴结阴性的II期和III期上皮性卵巢癌患者的影响。
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Survival effect of different lymph node staging methods on ovarian cancer: An analysis of 10 878 patients.不同淋巴结分期方法对卵巢癌生存效果的影响：10878 例患者分析。
Cancer Med. 2018 Sep;7(9):4315-4329. doi: 10.1002/cam4.1680. Epub 2018 Aug 18.
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J Gynecol Oncol. 2017 Sep;28(5):e68. doi: 10.3802/jgo.2017.28.e68. Epub 2017 Jun 13.
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Surgical manual of the Korean Gynecologic Oncology Group: ovarian, tubal, and peritoneal cancers.韩国妇科肿瘤学组手术手册：卵巢癌、输卵管癌和腹膜癌
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