Kulkarni S K, Stahl F W
Institute of Molecular Biology, University of Oregon, Eugene 97403.
Genetics. 1989 Oct;123(2):249-53. doi: 10.1093/genetics/123.2.249.
gam mutants of phage lambda carrying long palindromes fail to form plaques on wild-type Escherichia coli but do grow on strains that are mutant in the sbcC gene. gam + lambda carrying the same palindrome grow on both hosts and on a host deleted for the recB, C and D genes. These results suggest that the Gam protein of lambda, known to interact also with E. coli's recBCD protein, can interact with the product of the sbcC gene.
携带长回文序列的噬菌体λ的gam突变体无法在野生型大肠杆菌上形成噬菌斑,但能在sbcC基因突变的菌株上生长。携带相同回文序列的gam + λ在两种宿主以及缺失recB、C和D基因的宿主上都能生长。这些结果表明,已知λ的Gam蛋白也与大肠杆菌的recBCD蛋白相互作用,它也能与sbcC基因的产物相互作用。