Cheng L K
Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand; Department of Surgery, Vanderbilt University, Nashville, TN, USA.
Acta Physiol (Oxf). 2015 Feb;213(2):384-93. doi: 10.1111/apha.12406. Epub 2014 Nov 15.
This review provides an overview of our understanding of motility and slow wave propagation in the stomach. It begins by reviewing seminal studies conducted by Walter Cannon and Augustus Waller on in vivo motility and slow wave patterns. Then our current understanding of slow wave patterns in common laboratory animals and humans is presented. The implications of slow wave arrhythmic patterns that have been recorded in animals and patients suffering from gastroparesis are discussed. Finally, current challenges in experimental methods and techniques, slow wave modulation and the use of mathematical models are discussed.
本综述概述了我们对胃动力和慢波传播的理解。它首先回顾了沃尔特·坎农和奥古斯塔斯·沃勒关于体内动力和慢波模式的开创性研究。然后介绍了我们目前对常见实验动物和人类慢波模式的理解。讨论了在患有胃轻瘫的动物和患者中记录到的慢波心律失常模式的意义。最后，讨论了实验方法和技术、慢波调制以及数学模型应用方面当前面临的挑战。
