Chlebovská K, Chlebovský O
Radiobiol Radiother (Berl). 1989;30(5):453-8.
Quantitative changes of some selected serum proteins in rats irradiated with a single dose of 2 Gy neutrons were compared with protein changes in rats irradiated with an equal single neutron dose and subsequent continuous gamma irradiation using daily dose rate of 0.574 Gy up to the total dose of 6 Gy. On the basis of the values obtained from the diagrams of two-dimensional immunoelectrophoresis it was found that both irradiations entailed approximately equal quantitative changes of the serum concentrations of the proteins followed. The differences found concerned time intervals of the adjustment of the changes produced. After neutron irradiation reparation of the serum albumin occurred on 14th day, of A1-globulin concentrations on 28th day and of haptoglobin on 90th day, yet after combined neutron and gamma irradiation reparation of the changes in albumin on 15th and A1-globulin occurred on 40th day and in haptoglobin only on 100th day after neutron irradiation.
将单次剂量为2 Gy的中子辐照大鼠体内某些选定血清蛋白的定量变化，与接受相同单次中子剂量并随后进行连续γ辐照（每日剂量率为0.574 Gy，直至总剂量达6 Gy）的大鼠体内的蛋白变化进行了比较。根据二维免疫电泳图谱得出的值发现，两种辐照方式引起的下述血清蛋白浓度的定量变化大致相等。所发现的差异涉及产生变化后的调整时间间隔。中子辐照后，血清白蛋白在第14天出现修复，α1球蛋白浓度在第28天出现修复，触珠蛋白在第90天出现修复；而在中子和γ联合辐照后，白蛋白变化的修复在第15天出现，α1球蛋白变化的修复在第40天出现，触珠蛋白变化的修复仅在中子辐照后的第100天出现。
