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长期以递减的辐射剂量率持续照射的大鼠血清蛋白

Serum proteins in rats irradiated continuously over a long period at diminishing radiation dose rates.

作者信息

Chlebovská K, Chlebovský O

出版信息

Physiol Bohemoslov. 1986;35(2):134-9.

PMID:2941806
Abstract

The authors studied changes in serum protein concentrations in rats exposed 10 days to continuous irradiation at progressively diminishing dose rates imitating the radioactive decay of a fissile mixture, up to a total dose of 9 Gy, both during and up to 240 days after discontinuing irradiation. The prealbumin concentration (from the 6th day) and the A1-globulin concentration (from the 1st day) fell to 70% during irradiation. Afterwards, the A1-globulin level fell significantly up to the 28th day and then, from the 60th to the 240th day, rose again. During irradiation the serum haptoglobin concentration rose significantly from the 1st to the 10th day and the ceruloplasmin concentration on the 10th day. An increase in both protein concentrations (to 172% and 190%) was also observed on the 14th postirradiation day, after which the serum haptoglobin, ceruloplasmin and A1M concentration fell abruptly up to the 60th day.

摘要

作者研究了大鼠在模拟裂变混合物放射性衰变的逐渐递减剂量率下连续照射10天,直至总剂量达到9 Gy期间以及停止照射后240天内血清蛋白浓度的变化。照射期间,前白蛋白浓度(从第6天开始)和A1球蛋白浓度(从第1天开始)降至70%。此后,A1球蛋白水平在第28天前显著下降,然后从第60天到第240天再次上升。照射期间,血清触珠蛋白浓度从第1天到第10天显著上升,第10天铜蓝蛋白浓度也上升。照射后第14天还观察到两种蛋白浓度均增加(分别增至172%和190%),此后血清触珠蛋白、铜蓝蛋白和A1M浓度在第60天前急剧下降。

相似文献

1
Serum proteins in rats irradiated continuously over a long period at diminishing radiation dose rates.长期以递减的辐射剂量率持续照射的大鼠血清蛋白
Physiol Bohemoslov. 1986;35(2):134-9.
2
Character of changes in the serum proteins of continuously irradiated rats.连续照射大鼠血清蛋白变化的特征
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Determination of protein levels by quantitative immunoelectrophoresis in rats subjected to continuous irradiation.通过定量免疫电泳法测定持续照射大鼠的蛋白质水平。
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