Suppr超能文献

[夜间肾移植]

[Renal transplantation at night].

作者信息

Fockens M Matthijs, Alberts Victor P, Bemelman Frederike J, Idu Mirza M

机构信息

Academisch Medisch Centrum, Amsterdam.

出版信息

Ned Tijdschr Geneeskd. 2014;158:A7779.

Abstract

BACKGROUND

In renal transplantation, prolonged cold ischaemia time (CIT) increases the risk of delayed graft function, rejection and graft failure. To minimise CIT, renal transplantations are performed directly upon graft availability and often take place during the night. Night-time surgery is supposedly associated with an increased risk of surgical complications compared with daytime operations. The aim of this study was to assess the consequences of night-time renal transplantation on surgical complications and graft function.

METHOD

384 adult recipients of deceased-donor renal transplantations performed between January 2007 and June 2012 were retrospectively examined. Night-time renal transplantations were defined as surgery between 11 PM and 6 AM. The primary outcome was the occurrence of surgical complications. The secondary outcome was graft function.

RESULTS

No differences in surgical complications or graft function were observed among daytime and night-time groups. CIT was significantly increased in night-time renal transplantation (p < 0.001).

CONCLUSION

Night-time renal transplantation is not associated with an increased risk of surgical complications or graft failure, and can be considered a safe procedure. Given the need to minimise CIT, delaying the procedure until the morning is unjustified.

摘要

背景

在肾移植中,延长的冷缺血时间(CIT)会增加移植肾功能延迟恢复、排斥反应和移植失败的风险。为了尽量缩短CIT,肾移植在移植物可用时立即进行,且通常在夜间进行。与日间手术相比,夜间手术被认为会增加手术并发症的风险。本研究的目的是评估夜间肾移植对手术并发症和移植肾功能的影响。

方法

回顾性研究2007年1月至2012年6月期间进行的384例成年尸体供肾肾移植受者。夜间肾移植定义为晚上11点至早上6点之间进行的手术。主要结局是手术并发症的发生情况。次要结局是移植肾功能。

结果

日间组和夜间组在手术并发症或移植肾功能方面未观察到差异。夜间肾移植的CIT显著增加(p < 0.001)。

结论

夜间肾移植与手术并发症或移植失败风险增加无关,可被视为一种安全的手术方式。鉴于需要尽量缩短CIT,将手术推迟至上午是不合理的。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验