David M, Sandbank M, Lowe N J
Clin Exp Dermatol. 1989 May;14(3):230-2. doi: 10.1111/j.1365-2230.1989.tb00939.x.
Mucocutaneous side-effects from etretinate are common and are usually dose-dependent, whereas hypersensitivity drug eruptions are rare. Two patients are described in whom erythema multiforme-like eruptions appeared several days after oral intake of etretinate. In one patient etretinate rechallenge again produced the skin eruption. A brief review of the less common skin manifestations of etretinate therapy is provided.
依曲替酯的皮肤黏膜副作用很常见,且通常与剂量相关,而药物超敏反应性皮疹则较为罕见。本文描述了两名患者,他们在口服依曲替酯几天后出现了多形红斑样皮疹。其中一名患者再次服用依曲替酯后皮疹复发。本文还对依曲替酯治疗较少见的皮肤表现进行了简要综述。