Sesay Fatmata F, Hodges Mary H, Kamara Habib I, Turay Mohamed, Wolfe Adam, Samba Thomas T, Koroma Aminata S, Kamara Wogba, Fall Amadou, Mitula Pamela, Conteh Ishata, Maksha Nuhu, Jambai Amara
Helen Keller International, PO Box 369, Freetown, Sierra Leone
Helen Keller International, PO Box 369, Freetown, Sierra Leone.
Int Health. 2015 Jan;7(1):26-31. doi: 10.1093/inthealth/ihu073. Epub 2014 Oct 14.
In May 2012, the twice-yearly Maternal and Child Health Week (MCHW) integrated vitamin A supplementation (VAS) and supplementary measles vaccination to reach all children 6-59 months in Sierra Leone. Following the MCHW, a post event coverage survey was conducted to validate VAS coverage and assess adverse events following immunization.
Using the WHO Expanded Program on Immunization sampling methodology, 30 clusters were randomly selected using population proportionate to size sampling. Fourteen caregivers of children 6-59 months were interviewed per cluster for precision of ±5%. Responses were collected via mobile phones using EpiSurveyor.
Overall VAS and measles coverage was 91.9% and 91.6%, respectively, with no significant differences by age group, sex, religion or occupation. Major reasons given for not receiving VAS and measles vaccination were not knowing about the MCHW or being out of the area. Significantly more mild adverse events (fever, pain at injection site) were reported via the post event coverage survey (29.1%) than MCHW (0.01%) (p<0.0001).
The MCHW reached >90% of children in Sierra Leone with equitable coverage. Increased reporting of mild adverse events during the survey may be attributed to delayed onset after measles vaccination and/or direct inquiry from enumerators. Even mild adverse events following immunization requires strengthened reporting during and after vaccination campaigns.
2012年5月,塞拉利昂每半年一次的母婴健康周(MCHW)整合了维生素A补充剂(VAS)和麻疹补充疫苗接种,以覆盖所有6至59个月大的儿童。母婴健康周结束后,开展了一次活动后覆盖率调查,以核实维生素A补充剂的覆盖率,并评估免疫接种后的不良事件。
采用世界卫生组织扩大免疫规划抽样方法,使用按规模成比例抽样随机选择30个群组。每个群组采访14名6至59个月大儿童的看护人,精度为±5%。通过手机使用EpiSurveyor收集答复。
总体维生素A补充剂和麻疹疫苗接种覆盖率分别为91.9%和91.6%,按年龄组、性别、宗教或职业划分无显著差异。未接受维生素A补充剂和麻疹疫苗接种的主要原因是不了解母婴健康周或当时不在该地区。活动后覆盖率调查中报告的轻度不良事件(发热、注射部位疼痛)(29.1%)明显多于母婴健康周期间(0.01%)(p<0.0001)。
母婴健康周覆盖了塞拉利昂90%以上的儿童,覆盖率公平。调查期间轻度不良事件报告增加可能归因于麻疹疫苗接种后发病延迟和/或调查员的直接询问。即使是免疫接种后的轻度不良事件也需要在疫苗接种活动期间和之后加强报告。