Krouwer Jan S, Cembrowski George S
Krouwer Consulting, Sherborn, MA, USA
Alberta Health Services, Walter C. MacKenzie Center, Health Sciences Center, Edmonton, Canada.
J Diabetes Sci Technol. 2015 Jan;9(1):149-52. doi: 10.1177/1932296814554415. Epub 2014 Oct 14.
Traditional glucose error grids provide error limits for glucose meters. These criteria help to assess the meter's suitability to prevent acute injury. We present a rationale for an error grid that provides a different set of error limits to help prevent chronic injury in diabetes. For example, glucose values in the no treatment zone of a traditional error grid could be harmful in diabetic retinopathy. The same method comparison data informs both the acute and chronic injury error grids. All of the data are used in an acute injury error grid, whereas only long-term biases populate a chronic injury error grid. These biases can be due to reagent lots and patient specific interferences. An example of a chronic injury glucose error grid is provided using simulated data.
传统的血糖误差网格为血糖仪提供误差限度。这些标准有助于评估血糖仪预防急性损伤的适用性。我们提出一种误差网格的基本原理，该误差网格提供一组不同的误差限度，以帮助预防糖尿病患者的慢性损伤。例如，传统误差网格中无需治疗区域的血糖值可能对糖尿病视网膜病变有害。相同的方法比较数据同时用于急性损伤和慢性损伤误差网格。所有数据都用于急性损伤误差网格，而只有长期偏差用于填充慢性损伤误差网格。这些偏差可能源于试剂批次和患者特定干扰。使用模拟数据给出了一个慢性损伤血糖误差网格的示例。
