Vahid Dastjerdie Elaheh, Oskoui Mahvash, Sayanjali Elham, Tabatabaei Fahimeh Sadat
Department of Orthodontics, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Microbiology, Pasteur Institute of Iran, Tehran, Iran.
Iran J Pharm Res. 2012 Winter;11(1):77-82.
White spot lesions are observed in nearly 50% of patients undergoing orthodontic treatment. Long-lasting antibacterial properties of orthodontic cements can reduce this phenomenon. The aim of this research was to compare antimicrobial activity of three commercial glass ionomer cements with three commercial zinc phosphate cements, over time, against streptococcus mutans and candida albicans. Direct contact test (DCT) was used to evaluate the antibacterial and antifungal activity of products after 48 h and 7 days of incubation. The results demonstrated that all the cements presented antibacterial activity but the antibacterial activity of glass ionomer cements was more than that of zinc phosphate cements. Counts of C. albicans after 48 h were lower and statistically different in the GIC group in relation to the control groups. But no differences were observed between GIC and control groups at 7 days. Based on the results of this study, the antimicrobial and mainly antifungal effects of all the cements were so short.
在接受正畸治疗的患者中,近50%会出现白斑病变。正畸粘固剂的持久抗菌性能可减少这种现象。本研究的目的是比较三种商用玻璃离子粘固剂和三种商用磷酸锌粘固剂在不同时间对变形链球菌和白色念珠菌的抗菌活性。采用直接接触试验(DCT)评估产品在培养48小时和7天后的抗菌和抗真菌活性。结果表明,所有粘固剂均具有抗菌活性,但玻璃离子粘固剂的抗菌活性高于磷酸锌粘固剂。在48小时后,玻璃离子粘固剂组白色念珠菌的数量低于对照组,且具有统计学差异。但在7天时,玻璃离子粘固剂组与对照组之间未观察到差异。基于本研究结果,所有粘固剂的抗菌尤其是抗真菌作用都很短暂。