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经椎间孔硬膜外类固醇注射对神经根痛的影响:一项初步研究。

The effects of a forceful transforaminal epidural steroid injection on radicular pain: a preliminary study.

机构信息

Department of Anesthesiology and Pain Medicine, School of Medicine, Ewha Womans University, Seoul, Korea.

出版信息

Korean J Pain. 2014 Oct;27(4):334-8. doi: 10.3344/kjp.2014.27.4.334. Epub 2014 Oct 1.

Abstract

BACKGROUND

Lumbar transforaminal epidural steroid injections (TFESIs) are performed to provide symptom relief in patients with radicular pain. Recent articles suggested that injected volume itself have analgesic effects and higher volumes are associated with better outcomes. To date, few studies have been conducted to investigate the effects of volume. Therefore, well-designed controlled studies were necessary to confirm the effect of volume itself on pain relief. The purpose of this study was to examine the effectiveness of a forceful saline injection on lumbar TFESI using non-particulate steroids.

METHODS

Fifty consecutive patients with lumbar radicular pain were enrolled. The participants were allocated into one of two groups: dexamethasone with volume (Group DV) and dexamethasone alone (Group DO). The volume was delivered by a forceful injection of 5ml of normal saline. The primary end-point for this study was a VAS pain score and modified MacNab score indicating the rate of effectiveness at the four-week follow-up.

RESULTS

There were no significant post-procedural VAS differences between two groups (P = .252). The effectiveness rate among the patients was 47.8% in DV group, 34.8% in DO group, measured by modified MacNab score. The difference was not statistically significant (P = .117).

CONCLUSIONS

A forceful saline injection did not have a significant effect during the treatment of radicular pain. Further studies with greater volumes and with additional techniques would offer a more conclusive perspective.

摘要

背景

腰椎经椎间孔硬膜外类固醇注射(TFESI)用于为神经根痛患者提供症状缓解。最近的一些文章表明,注射量本身具有镇痛作用,并且更大的注射量与更好的效果相关。迄今为止,很少有研究探讨注射量的影响。因此,需要进行精心设计的对照研究来证实注射量本身对疼痛缓解的影响。本研究的目的是研究使用非颗粒类固醇强力生理盐水注射对腰椎 TFESI 的效果。

方法

连续纳入 50 例患有腰椎神经根痛的患者。将参与者分配到两组之一:地塞米松加容量组(DV 组)和地塞米松单独组(DO 组)。通过强力注射 5ml 生理盐水来输送容量。本研究的主要终点是 VAS 疼痛评分和改良 MacNab 评分,以在四周随访时表示有效性的比率。

结果

两组之间术后 VAS 差异无统计学意义(P =.252)。DV 组的有效率为 47.8%,DO 组为 34.8%,通过改良 MacNab 评分测量。差异无统计学意义(P =.117)。

结论

在神经根痛的治疗中,强力生理盐水注射没有显著效果。进一步研究更大的容量和额外的技术将提供更具结论性的观点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/250a/4196498/90f3b09a5653/kjpain-27-334-g001.jpg

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