Department of Anaesthesia, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, India.
Department of Anaesthesia, Post Graduate Institute of Medical Education and research, Chandigarh, India.
Korean J Pain. 2014 Oct;27(4):353-9. doi: 10.3344/kjp.2014.27.4.353. Epub 2014 Oct 1.
Epidural steroid injections are an accepted procedure for the conservative management of chronic backache caused by lumbar disc pathology. The purpose of this study was to evaluate the epidurographic findings for the midline, transforaminal and parasagittal approaches in lumbar epidural steroid injections, and correlating them with the clinical improvement.
Sixty chronic lower back pain patients with unilateral radiculitis from a herniated/degenerated disc were enrolled. After screening the patients according to the exclusion criteria and randomly allocating them to 3 groups of 20 patients, fluoroscopic contrast enhanced epidural steroids were injected via midline (group 1), transforaminal (group 2) and parasagittal interlaminar (group 3) approaches at the level of the pathology. The fluoroscopic patterns of the three groups were studied and correlated with the clinical improvement measured by the VAS over the next 3 months; any incidences of complications were recorded.
The transforaminal group presented better results in terms of VAS reduction than the midline and parasagittal approach groups (P < 0.05). The epidurography showed a better ventral spread for both the transforaminal (P < 0.001) and the paramedian approaches (P < 0.05), as compared to the midline approach. The nerve root filling was greater in the transforaminal group (P < 0.001) than in the other two groups. The ventral spread of the contrast agent was associated with improvement in the VAS score and this difference was statistically significant in group 1 (P < 0.05), and highly significant in groups 2 and 3 (P < 0.001). In all the groups, any complications observed were transient and minor.
The midline and paramedian approaches are technically easier and statistically comparable, but clinically less efficacious than the transforaminal approach. The incidence of ventral spread and nerve root delineation show a definite correlation with clinical improvement. However, an longer follow-up period is advisable for a better evaluation of the actual outcom.
硬膜外类固醇注射是一种被接受的方法,用于治疗由腰椎间盘病变引起的慢性腰痛。本研究的目的是评估腰椎硬膜外类固醇注射的中线、经椎间孔和旁正中入路的硬膜外造影结果,并将其与临床改善相关联。
招募了 60 名单侧神经根炎的慢性下腰痛患者,这些患者来自于突出/变性的椎间盘。在根据排除标准筛选患者并将其随机分配到 3 组(每组 20 名患者)后,通过中线(第 1 组)、经椎间孔(第 2 组)和旁正中椎间(第 3 组)途径在病变水平处注射荧光增强硬膜外类固醇。研究了三组的荧光模式,并将其与接下来 3 个月内 VAS 测量的临床改善相关联;记录任何并发症的发生情况。
与中线和旁正中入路组相比,经椎间孔组在 VAS 降低方面的结果更好(P < 0.05)。与中线入路相比,经椎间孔(P < 0.001)和旁正中途径(P < 0.05)的硬膜外造影显示出更好的腹侧扩散。神经根充盈在经椎间孔组中更大(P < 0.001)。造影剂的腹侧扩散与 VAS 评分的改善相关,在第 1 组中这种差异具有统计学意义(P < 0.05),在第 2 组和第 3 组中具有高度统计学意义(P < 0.001)。在所有组中,观察到的任何并发症都是短暂和轻微的。
中线和旁正中途径在技术上更容易,统计学上可比,但在临床上不如经椎间孔途径有效。腹侧扩散和神经根描绘的发生率与临床改善有明确的相关性。然而,为了更好地评估实际结果,建议进行更长时间的随访。