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隐源性卒中:一项诊断挑战。

Cryptogenic stroke: A diagnostic challenge.

作者信息

Yaghi Shadi, Elkind Mitchell S V

机构信息

Department of Neurology, College of Physicians and Surgeons (SY, MSVE), and Department of Epidemiology, Mailman School of Public Health (MSVE), Columbia University, New York, NY.

出版信息

Neurol Clin Pract. 2014 Oct;4(5):386-393. doi: 10.1212/CPJ.0000000000000086.

DOI:10.1212/CPJ.0000000000000086
PMID:25317376
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4196459/
Abstract

Cryptogenic, or unexplained, stroke is present in about 30%-40% of ischemic stroke patients. Pursuing a stroke mechanism is important in such patients to better choose therapy to reduce the stroke recurrence risk. Intracranial vessel imaging and cardiac evaluation with transesophageal echocardiogram and outpatient cardiac monitoring may help identify the stroke mechanism. This article highlights the diagnostic yield of various tests in identifying a stroke mechanism in stroke patients whose initial diagnostic evaluation is negative, and the implications for treatment.

摘要

隐源性卒中,即不明原因的卒中,约占缺血性卒中患者的30%-40%。对于此类患者,探寻卒中机制对于更好地选择治疗方法以降低卒中复发风险至关重要。颅内血管成像以及经食管超声心动图和门诊心脏监测等心脏评估可能有助于确定卒中机制。本文重点介绍了在初始诊断评估为阴性的卒中患者中,各种检查在确定卒中机制方面的诊断价值以及对治疗的影响。

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Cryptogenic stroke: A diagnostic challenge.隐源性卒中:一项诊断挑战。
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本文引用的文献

1
Cryptogenic stroke and underlying atrial fibrillation.隐匿性脑卒中与潜在的心房颤动。
N Engl J Med. 2014 Jun 26;370(26):2478-86. doi: 10.1056/NEJMoa1313600.
2
Atrial fibrillation in patients with cryptogenic stroke.不明原因卒中患者的心房颤动。
N Engl J Med. 2014 Jun 26;370(26):2467-77. doi: 10.1056/NEJMoa1311376.
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Clopidogrel plus aspirin versus warfarin in patients with stroke and aortic arch plaques.氯吡格雷联合阿司匹林与华法林治疗合并主动脉弓斑块的缺血性脑卒中患者的疗效比较
Stroke. 2014 May;45(5):1248-57. doi: 10.1161/STROKEAHA.113.004251. Epub 2014 Apr 3.
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Systematic review of percutaneous closure versus medical therapy in patients with cryptogenic stroke and patent foramen ovale.隐源性卒中合并卵圆孔未闭患者经皮封堵与药物治疗的系统评价
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[High performance of an implantable Holter monitor in the detection of concealed paroxysmal atrial fibrillation in patients with cryptogenic stroke and a suspected embolic mechanism].[植入式动态心电图监测仪在检测不明原因卒中且怀疑有栓塞机制患者隐匿性阵发性房颤中的高性能表现]
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Stroke. 2013 Mar;44(3):870-947. doi: 10.1161/STR.0b013e318284056a. Epub 2013 Jan 31.
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