Bartholomay Eduardo, Polli Ismael, Borges Anibal Pires, Kalil Carlos, Arroque André, Kohler Ilmar, Danzmann Luiz Cláudio
Universidade Luterana do Brasil, Cardiology, Porto Alegre, RS, Brazil.
Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Cardiology, Porto Alegre, RS, Brazil.
Clinics (Sao Paulo). 2014 Sep;69(9):615-20. doi: 10.6061/clinics/2014(09)07.
Atrial fibrillation is the most common sustained arrhythmia and is associated with poor outcomes, including stroke. The ability of anticoagulation therapy to reduce the risk of stroke has been well established; however, the prevalence of anticoagulation therapy use in the Public Health System is unknown. The aim of this study is to evaluate both the prevalence of anticoagulation therapy among patients with atrial fibrillation and the indications for the treatment.
In this cross-sectional study, we included consecutive patients who had atrial fibrillation documented by an electrocardiogram performed between September 2011 and March 2012 at a university hospital of the Public Health System. The variables analyzed included the risk of a thromboembolic event and/or bleeding, the use of antiplatelet or anticoagulation therapy, the location where the electrocardiogram report was initially reviewed and the specialty of the physician who initially reviewed it.
We included 162 patients (mean age 68.9 years, 56% men). Hypertension (90.1%), heart failure (53.4%) and stroke (38.9%) were the most prevalent diseases found. Only 50.6% of the patients knew that they had atrial fibrillation. Regarding the use of therapy, only 37.6% of patients classified as high risk according to the CHADS2 scores and 35.5% according to the CHA2DS2VASc used oral anticoagulation. A presumptive diagnosis of heart failure and the fact that the electrocardiogram was evaluated by a cardiologist were the only independent predictors of the use of anticoagulants.
Our study found a low prevalence of oral anticoagulation therapy among patients with atrial fibrillation and an indication for stroke prophylaxis for the use of this therapy, including among those with high CHADS2 and CHA2DS2VASc scores.
心房颤动是最常见的持续性心律失常,与包括中风在内的不良后果相关。抗凝治疗降低中风风险的能力已得到充分证实;然而,公共卫生系统中抗凝治疗的使用情况尚不清楚。本研究的目的是评估心房颤动患者中抗凝治疗的患病率以及治疗指征。
在这项横断面研究中,我们纳入了2011年9月至2012年3月在公共卫生系统的一家大学医院通过心电图记录确诊为心房颤动的连续患者。分析的变量包括血栓栓塞事件和/或出血的风险、抗血小板或抗凝治疗的使用、心电图报告最初审阅的地点以及最初审阅报告的医生的专业。
我们纳入了162例患者(平均年龄68.9岁,56%为男性)。高血压(90.1%)、心力衰竭(53.4%)和中风(38.9%)是最常见的疾病。只有50.6%的患者知道自己患有心房颤动。关于治疗的使用,根据CHADS2评分归类为高危的患者中只有37.6%,根据CHA2DS2VASc评分归类为高危的患者中只有35.5%使用了口服抗凝药。心力衰竭的初步诊断以及心电图由心脏病专家评估是使用抗凝剂的唯一独立预测因素。
我们的研究发现心房颤动患者中口服抗凝治疗的患病率较低,且对于该治疗用于中风预防存在指征,包括在CHADS2和CHA2DS2VASc评分较高的患者中。