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Cell memory and adaptation in chemotaxis.

作者信息

Huang Chuan-Hsiang, Iglesias Pablo A

机构信息

Department of Cell Biology, The Johns Hopkins School of Medicine, Baltimore, MD 21205; and

Department of Cell Biology, The Johns Hopkins School of Medicine, Baltimore, MD 21205; and Department of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218

出版信息

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15287-8. doi: 10.1073/pnas.1418077111. Epub 2014 Oct 15.

DOI:10.1073/pnas.1418077111
PMID:25319263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4217466/
Abstract
摘要

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本文引用的文献

1
Cellular memory in eukaryotic chemotaxis.真核生物趋化作用中的细胞记忆。
Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14448-53. doi: 10.1073/pnas.1412197111. Epub 2014 Sep 23.
2
An excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration.兴奋信号整合器与空闲细胞骨架振荡器耦合，以驱动细胞迁移。
Nat Cell Biol. 2013 Nov;15(11):1307-16. doi: 10.1038/ncb2859. Epub 2013 Oct 20.
3
Interaction of motility, directional sensing, and polarity modules recreates the behaviors of chemotaxing cells.运动性、定向感应和极性模块的相互作用再现了趋化性细胞的行为。
PLoS Comput Biol. 2013;9(7):e1003122. doi: 10.1371/journal.pcbi.1003122. Epub 2013 Jul 4.
4
Membrane tension maintains cell polarity by confining signals to the leading edge during neutrophil migration.细胞膜张力通过将信号限制在中性粒细胞迁移过程中的前缘来维持细胞极性。
Cell. 2012 Jan 20;148(1-2):175-88. doi: 10.1016/j.cell.2011.10.050.
5
Calling heads from tails: the role of mathematical modeling in understanding cell polarization.明辨正反：数学建模在理解细胞极化中的作用
Curr Opin Cell Biol. 2009 Feb;21(1):74-81. doi: 10.1016/j.ceb.2009.01.001. Epub 2009 Jan 23.
6
PI3-kinase signaling contributes to orientation in shallow gradients and enhances speed in steep chemoattractant gradients.磷脂酰肌醇-3激酶信号传导有助于在浅梯度中定向，并在陡峭的趋化因子梯度中提高速度。
J Cell Sci. 2008 Nov 1;121(Pt 21):3589-97. doi: 10.1242/jcs.031781. Epub 2008 Oct 7.
7
Cellular asymmetry and individuality in directional sensing.定向感知中的细胞不对称性与个体性。
Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11549-54. doi: 10.1073/pnas.0601909103. Epub 2006 Jul 24.
8
Diffusion-limited phase separation in eukaryotic chemotaxis.真核生物趋化作用中的扩散限制相分离
Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):16927-32. doi: 10.1073/pnas.0503974102. Epub 2005 Nov 16.
9
Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement.前沿的局部Ras信号传导调节PI3K、细胞极性和细胞定向运动。
J Cell Biol. 2004 Nov 8;167(3):505-18. doi: 10.1083/jcb.200406177.
10
Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton.趋化因子诱导的磷脂酰肌醇-3,4,5-三磷酸积累在空间上被放大并产生适应性变化，且与肌动蛋白细胞骨架无关。
Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):8951-6. doi: 10.1073/pnas.0402152101. Epub 2004 Jun 7.