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虫霉病:一种具有挑战性的新兴疾病。

Entomophthoromycosis: a challenging emerging disease.

作者信息

El-Shabrawi Mortada H F, Arnaout Heba, Madkour Lamiaa, Kamal Naglaa Mohamed

机构信息

Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo, Egypt.

出版信息

Mycoses. 2014 Dec;57 Suppl 3:132-7. doi: 10.1111/myc.12248. Epub 2014 Oct 16.

DOI:10.1111/myc.12248
PMID:25319641
Abstract

Entomophthoromycosis is a rare fungal infection that may affect immunocompetent hosts; predominantly in tropical and subtropical regions. Recently, the importance of this emerging mycosis has increased and the scope of its manifestations has been expanded. These manifestations; however, may masquerade as other clinical entities. Prompt diagnosis of this infection requires a high index of suspicion. Although histopathological examination and cultures are the gold standard diagnostic tools; molecular diagnosis is now available and started to play an important role. The cornerstone treatment is prolonged anti-fungal therapy along with surgical debridement. More awareness of this mycosis is warranted for definitive diagnosis and implementation of early proper therapeutic strategies.

摘要

虫霉病是一种罕见的真菌感染,可能影响免疫功能正常的宿主,主要发生在热带和亚热带地区。近年来,这种新发真菌病的重要性日益增加,其临床表现范围也有所扩大。然而,这些表现可能会伪装成其他临床病症。及时诊断这种感染需要高度的怀疑指数。尽管组织病理学检查和培养是金标准诊断工具,但分子诊断现已可用并开始发挥重要作用。基础治疗是延长抗真菌治疗并辅以手术清创。为了进行明确诊断和实施早期适当的治疗策略,有必要提高对这种真菌病的认识。

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