Wolf J E, Rose-Pittet L, Page E, Borrel E, Bertrand B, Lebas J F, Machecourt J, Coulomb M, Denis B
Clinique cardiologique et urgences cardiologiques, CHU, Grenoble.
Arch Mal Coeur Vaiss. 1989 Oct;82(10):1711-7.
Seven patients with arrhythmogenic right ventricular dysplasia were explored by magnetic resonance imaging (MRI), using the spin-echo technique (TR = the patient's own RR cycle; TE = 28 ms, 56 ms, 84 ms) with multiple, contiguous, 7 to 10 mm thick sections performed in two planes: axial plus sagittal or frontal planes. In 5 out of 7 patients, MRI showed dysplastic lesions in the right ventricular wall presenting typically as fat-like high signals contrasting with the normal myocardium. In 2 patients, no lesion was clearly visualized. The parietal lesions were located in the anterior wall of the right ventricle and conus arteriosus in 5 cases and in the lower wall of the right ventricle in one patient who had two dysplastic areas. In 3 patients the lesions extended up to the tip of the interventricular septum and of the left ventricle. In the 2 patients whose lesions were most extensive, their predominance in the subepicardial region and the concordance between the sites of abnormalities at MRI and angiography were clearly observed. Thus, despite its present technical limitations MRI seems to be one of the first techniques capable of visualizing the parietal lesions in patients with arrhythmogenic right ventricular dysplasia.
对7例致心律失常性右室发育不良患者进行了磁共振成像(MRI)检查,采用自旋回波技术(重复时间(TR)=患者自身的RR间期;回波时间(TE)=28毫秒、56毫秒、84毫秒),在两个平面上进行多幅连续的、厚度为7至10毫米的切片扫描:轴位加矢状位或额状位。7例患者中有5例,MRI显示右室壁发育异常病变,典型表现为与正常心肌形成对比的脂肪样高信号。2例患者未清晰显示病变。壁层病变位于右室前壁和动脉圆锥5例,位于右室下壁1例(该患者有两个发育异常区域)。3例患者病变延伸至室间隔尖端和左室。在病变最广泛的2例患者中,明显观察到病变在心肌下区域占优势,且MRI与血管造影的异常部位一致。因此,尽管目前MRI存在技术局限性,但它似乎是能够显示致心律失常性右室发育不良患者壁层病变的首批技术之一。