Adequate intake of biotin in pregnancy: why bother?
作者信息
Mock Donald M
机构信息
University of Arkansas for Medical Sciences, Department of Biochemistry and Molecular Biology, Little Rock, AR
出版信息
J Nutr. 2014 Dec;144(12):1885-6. doi: 10.3945/jn.114.203356. Epub 2014 Oct 15.
Abstract
摘要
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Adequate intake of biotin in pregnancy: why bother?孕期充足摄入生物素：为何要这么做？
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2
Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.怀孕和哺乳会改变食用控制饮食的女性生物素代谢的生物标志物。
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3
Urinary excretion of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans.3-羟基异戊酰基辅酶 A 尿排泄量是人类边缘生物素缺乏的早期和敏感指标。
J Nutr. 2011 Mar;141(3):353-8. doi: 10.3945/jn.110.135772. Epub 2011 Jan 19.
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Plasma concentration of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans.血浆中 3-羟基异戊酰肉碱浓度是人类边缘性生物素缺乏的早期敏感指标。
Am J Clin Nutr. 2010 Dec;92(6):1399-405. doi: 10.3945/ajcn.110.002543. Epub 2010 Oct 13.
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Carnitine, mitochondrial function and therapy.肉碱、线粒体功能与治疗。
Adv Drug Deliv Rev. 2009 Nov 30;61(14):1353-62. doi: 10.1016/j.addr.2009.04.024. Epub 2009 Aug 26.
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Marginal biotin deficiency is common in normal human pregnancy and is highly teratogenic in mice.边缘性生物素缺乏在正常人类妊娠中很常见，且在小鼠中具有高度致畸性。
J Nutr. 2009 Jan;139(1):154-7. doi: 10.3945/jn.108.095273. Epub 2008 Dec 3.
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Biochemical findings in common inborn errors of metabolism.常见先天性代谢缺陷的生化检查结果
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Marginal maternal biotin deficiency in CD-1 mice reduces fetal mass of biotin-dependent carboxylases.CD-1小鼠母体边缘性生物素缺乏会降低生物素依赖性羧化酶的胎儿质量。
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Marginal biotin deficiency is teratogenic in ICR mice.边缘性生物素缺乏对ICR小鼠具有致畸性。
J Nutr. 2003 Aug;133(8):2519-25. doi: 10.1093/jn/133.8.2519.
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Marginal biotin deficiency during normal pregnancy.正常孕期边缘性生物素缺乏
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