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[多不饱和磷脂酰胆碱与胆汁脂质成分]

[Polyunsaturated phosphatidylcholine and bile lipid composition].

作者信息

Salvioli G, Lugli R

出版信息

Clin Ter. 1989 Nov 30;131(4):219-24.

PMID:2532091
Abstract

The lipid composition of bile and the molar percentages of its components (cholesterol, lecithin [Lec], and bile salts) are influenced by diet composition (for example the content of cholesterol) and during fasting. Molecular species of Lec can be affected by the species of dietary fatty acids (a high n-3 fatty acid content in the diet increases their proportion in biliary Lec). The administration of polyunsaturated Lec (EPL), rich in 18:2-18:2-PC, increases the percentage of linoleic acid at position 2 of biliary lecithin, which is often reduced in subjects with cholesterol gallstones.

摘要

胆汁的脂质组成及其成分(胆固醇、卵磷脂[Lec]和胆盐)的摩尔百分比受饮食组成(例如胆固醇含量)和禁食的影响。Lec的分子种类可受膳食脂肪酸种类的影响(饮食中高含量的n-3脂肪酸会增加其在胆汁Lec中的比例)。给予富含18:2-18:2-PC的多不饱和Lec(EPL)可增加胆汁卵磷脂2位亚油酸的百分比,而胆固醇结石患者的该比例通常会降低。

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