Stefanini G, Zunarelli P, Mazzetti M, Biagi P, Bordoni A, Petio C, Amorati P, Hrelia S, Gasbarrini G, Turchetto E
Clin Ter. 1989 Nov 30;131(4):233-6.
The aim of this study is to assess "in vitro" the influence of polyunsaturated phosphatidylcholine on the erythrocyte membrane fluidity in alcoholics (greater than 180 g/die) and control subjects (less than 50 g/die), investigated by the evaluation of fluorescent polarization of DPH. In both groups a significant increase of membrane microviscosity was observed after incubation with 0.04 microM and 0.08 microM of PC compared to baseline values.
本研究的目的是通过评估DPH的荧光偏振，“体外”评估多不饱和磷脂酰胆碱对酗酒者（每日饮酒量大于180克）和对照受试者（每日饮酒量小于50克）红细胞膜流动性的影响。与基线值相比，在两组中，用0.04微摩尔和0.08微摩尔的PC孵育后，均观察到膜微粘度显著增加。
